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  1. Toxic epidermal necrolysis (TEN) is a rare acute life-threatening mucocutaneous disorder that is mostly drug-related (80%–95%). It is clinically characterized as a widespread sloughing of the skin and mucosa. ...

    Authors: Ji-Jie Huang, Shu-Xiang Ma, Xue Hou, Zhao Wang, Yin-Duo Zeng, Tao Qin, Xiao-Xiao Dinglin and Li-Kun Chen

    Citation: Chinese Journal of Cancer 2015 34:340020094

    Content type: Case Research

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  2. For children with stage II testicular malignant germ cell tumors (MGCT), the survival is good with surgery and adjuvant chemotherapy. However, there is limited data on surgical results for cases in which there...

    Authors: Su-Ying Lu, Xiao-Fei Sun, Zi-Jun Zhen, Zi-Ke Qin, Zhuo-Wei Liu, Jia Zhu, Juan Wang and Fei-Fei Sun

    Citation: Chinese Journal of Cancer 2015 34:340020086

    Content type: Original Article

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  3. The time to complete or partial (objective) response to radiotherapy in patients with hepatocellular carcinoma (HCC) is variable; thus, the reported frequency of these responses depends on the length of follow...

    Authors: Moonkyoo Kong and Seong Eon Hong

    Citation: Chinese Journal of Cancer 2015 34:340020079

    Content type: Original Article

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  4. Interim 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (I-PET/CT) is a powerful tool for monitoring the response to therapy in diffuse large B-cell lymphoma (DLBCL). This retrospect...

    Authors: Xu Zhang, Wei Fan, Zhong-Jun Xia, Ying-Ying Hu, Xiao-Ping Lin, Ya-Rui Zhang, Zhi-Ming Li, Pei-Yan Liang and Yuan-Hua Li

    Citation: Chinese Journal of Cancer 2015 34:340020070

    Content type: Original Article

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  5. Protein tyrosine phosphatases (PTPs) play an important role in regulating cell signaling events in coordination with tyrosine kinases to control cell proliferation, apoptosis, survival, migration, and invasion...

    Authors: Yu Du and Jennifer R. Grandis

    Citation: Chinese Journal of Cancer 2015 34:340020061

    Content type: Review

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  6. Advances in cancer treatment allow women to be cured and live longer. However, the necessary chemotherapy and radiotherapy regimens have a negative impact on future fertility. Oncofertility has emerged as a ne...

    Authors: Cristina Sigismondi, Enrico Papaleo, Paola Viganò, Simona Vailati, Massimo Candiani, Jessica Ottolina, Valentina E. Di Mattei and Giorgia Mangili

    Citation: Chinese Journal of Cancer 2015 34:340010056

    Content type: Original Article

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  7. Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cor...

    Authors: Mojgan Devouassoux-Shisheboran and Catherine Genestie

    Citation: Chinese Journal of Cancer 2015 34:340010050

    Content type: Review

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  8. Epithelial ovarian cancer (OC) is a common gynecologic malignancy in women. The standard treatment for OC is maximal cytoreductive surgical debulking followed by platinum-based chemotherapy. Despite the high r...

    Authors: José Antonio López-Guerrero, Ignacio Romero and Andrés Poveda

    Citation: Chinese Journal of Cancer 2015 34:340010041

    Content type: Review

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  9. Metastasis is the main cause of cancer mortality. One of the initiating events of cancer metastasis of epithelial tumors is epithelial-to-mesenchymal transition (EMT), during which cells dedifferentiate from a...

    Authors: Yan Sun, Fei Guo, Marina Bagnoli, Feng-Xia Xue, Bao-Cun Sun, Ilya Shmulevich, Delia Mezzanzanica, Ke-Xin Chen, Anil K. Sood, Da Yang and Wei Zhang

    Citation: Chinese Journal of Cancer 2015 34:340010028

    Content type: Review

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  10. Ovarian cancer remains a major issue for gynecological oncologists, and most patients are diagnosed when the disease is already advanced with a poor chance of survival. Debulking surgery followed by platinum-t...

    Authors: Chiara Della Pepa, Giuseppe Tonini, Carmela Pisano, Marilena Di Napoli, Sabrina Chiara Cecere, Rosa Tambaro, Gaetano Facchini and Sando Pignata

    Citation: Chinese Journal of Cancer 2015 34:340010017

    Content type: Review

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  11. In this issue of the Chinese Journal of Cancer, European, American, and Chinese experts review the current management and future perspectives of epithelial ovarian cancer (EOC), the leading cause of gynecological...

    Authors: Delia Mezzanzanica

    Citation: Chinese Journal of Cancer 2015 34:340010001

    Content type: Editorial

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  12. Hepatitis B virus (HBV) reactivation has been reported in B-cell lymphoma patients with resolved hepatitis B (hepatitis B surface antigen [HBsAg]-negative and hepatitis B core antibody [HBcAb]-positive). This ...

    Authors: Kai-Lin Chen, Jie Chen, Hui-Lan Rao, Ying Guo, Hui-Qiang Huang, Liang Zhang, Jian-Yong Shao, Tong-Yu Lin, Wen-Qi Jiang, De-Hui Zou, Li-Yang Hu, Michael Lucas Wirian and Qing-Qing Cai

    Citation: Chinese Journal of Cancer 2015 34:18

    Content type: Original article

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  13. Hepatocellular adenomas (HCAs), with a risk of malignant transformation into hepatocellular carcinoma (HCC), classically develop in young women who are taking oral contraceptives. It is now clear that HCAs may...

    Authors: Song-Lin An, Li-Ming Wang, Wei-Qi Rong, Fan Wu, Wei Sun, Wei-Bo Yu, Li Feng, Fa-Qiang Liu, Fei Tian and Jian-Xiong Wu

    Citation: Chinese Journal of Cancer 2015 34:17

    Content type: Original article

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  14. It is important to decrease the radiation exposure of normal tissue in intensity-modulated radiation therapy (IMRT). Minimizing planning target volume (PTV) margins with more precise target localization techni...

    Authors: Yan-Ping Mao, Wen-Jing Yin, Rui Guo, Guang-Shun Zhang, Jian-Lan Fang, Feng Chi, Zhen-Yu Qi, Meng-Zhong Liu, Jun Ma and Ying Sun

    Citation: Chinese Journal of Cancer 2015 34:16

    Content type: Original article

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  15. In the past several decades, declining incidences of nasopharyngeal carcinoma (NPC) have been observed in Chinese populations in Hong Kong, Taiwan, Los Angeles, and Singapore. A previous study indicated that t...

    Authors: Li-Fang Zhang, Yan-Hua Li, Shang-Hang Xie, Wei Ling, Sui-Hong Chen, Qing Liu, Qi-Hong Huang and Su-Mei Cao

    Citation: Chinese Journal of Cancer 2015 34:15

    Content type: Original article

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  16. Most hepatocellular carcinomas (HCC) develop in a background of underlying liver disease including chronic hepatitis B. However, the effect of antiviral therapy on the long-term outcome of patients with hepati...

    Authors: Zhong-Guo Zhou, Xing-Rong Zheng, Qian Zhou, Ming Shi, Yao-Jun Zhang, Rong-Ping Guo, Yun-Fei Yuan, Min-Shan Chen, Xiao-Jun Lin, Xiang-Ming Lao and Sheng-Ping Li

    Citation: Chinese Journal of Cancer 2015 34:14

    Content type: Original article

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  17. Breast cancer is a leading tumor with a high mortality in women. This study examined the spatio-temporal distribution of the incidence of female breast cancer in Shenzhen between 2007 and 2012.

    Authors: Hai-Bin Zhou, Sheng-Yuan Liu, Lin Lei, Zhong-Wei Chen, Ji Peng, Ying-Zhou Yang and Xiao-Li Liu

    Citation: Chinese Journal of Cancer 2015 34:13

    Content type: Original Article

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  18. An increasing number of targeted drugs have been tested for the treatment of nasopharyngeal carcinoma (NPC). However, targeted therapy-related oncogenic mutations have not been fully evaluated. This study aime...

    Authors: Jian-Wei Zhang, Tao Qin, Shao-Dong Hong, Jing Zhang, Wen-Feng Fang, Yuan-Yuan Zhao, Yun-Peng Yang, Cong Xue, Yan Huang, Hong-Yuan Zhao, Yu-Xiang Ma, Zhi-Huang Hu, Pei-Yu Huang and Li Zhang

    Citation: Chinese Journal of Cancer 2015 34:10

    Content type: Original article

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  19. Oncogenic activation of the K-ras gene occurs in >90% of pancreatic ductal carcinoma and plays a critical role in the pathogenesis of this malignancy. Increase of reactive oxygen species (ROS) has also been obser...

    Authors: Peng Wang, Yi-Chen Sun, Wen-Hua Lu, Peng Huang and Yumin Hu

    Citation: Chinese Journal of Cancer 2015 34:8

    Content type: Original article

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  20. ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) proteins are efflux transporters that couple the energy derived from ATP hydrolysis to the translocation of toxic substances...

    Authors: Rishil J Kathawala, Yi-Jun Wang, Suneet Shukla, Yun-Kai Zhang, Saeed Alqahtani, Amal Kaddoumi, Suresh V Ambudkar, Charles R Ashby Jr and Zhe-Sheng Chen

    Citation: Chinese Journal of Cancer 2015 34:5

    Content type: Research

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  21. Patients with nasopharyngeal carcinoma (NPC) sporadically develop abnormal adenoids. Nasopharyngeal adenoids are usually included in the gross tumor volume (GTV) but may have different therapeutic responses th...

    Authors: Yao-Pan Wu, Pei-Qiang Cai, Li Tian, Jie-Hua Xu, Richard Alan Mitteer Jr, Yi Fan and Zhenfeng Zhang

    Citation: Chinese Journal of Cancer 2015 34:4

    Content type: Original article

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  22. In the adult human breast, hyperplastic enlarged lobular unit (HELU) and atypical ductal hyperplasia (ADH) are two common abnormalities that frequently coexist with ductal carcinoma in situ (DCIS). For this reaso...

    Authors: Danila Coradini, Patrizia Boracchi, Saro Oriana, Elia Biganzoli and Federico Ambrogi

    Citation: Chinese Journal of Cancer 2015 34:3

    Content type: Research

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  23. Polymorphisms in DNA repair genes may alter DNA repair capacity and, consequently, lead to genetic instability and carcinogenesis. Several studies have investigated the association of the Asp312Asn and Lys751G...

    Authors: Shen Chen, Jin-Hong Zhu, Fang Wang, Shao-Yi Huang, Wen-Qiong Xue, Zhuo Cui, Jing He and Wei-Hua Jia

    Citation: Chinese Journal of Cancer 2015 34:2

    Content type: Original article

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  24. Thrombocytosis has been identified as an unfavorable prognostic factor in several types of cancer. This study aimed to evaluate the prognostic value of pretreatment platelet count in association with the TNM s...

    Authors: Yu-Pei Chen, Bing-Cheng Zhao, Chen Chen, Lu-Jun Shen, Jin Gao, Zhuo-Yao Mai, Meng-Kun Chen, Gang Chen, Fang Yan, Su Liu and Yun-Fei Xia

    Citation: Chinese Journal of Cancer 2015 34:1

    Content type: Original Article

    Published on:

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