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  1. Content type: Original article

    Plasma circulating tumor DNA (ctDNA) is an ideal approach to detecting the epidermal growth factor receptor (EGFR) T790M mutation, which is a major mechanism of resistance to first-generation EGFR-tyrosine kinase...

    Authors: Shirong Zhang, Lucheng Zhu, Bing Xia, Enguo Chen, Qiong Zhao, Xiaochen Zhang, Xueqin Chen, Xufeng Chen and Shenglin Ma

    Citation: Cancer Communications 2018 38:28

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  2. Content type: Original article

    Neoadjuvant chemoradiotherapy followed by surgery is recommended as the standard of care for locally advanced rectal cancer, reducing local recurrence but not distant metastasis. Intensified systemic therapy i...

    Authors: Xin Yu, Qiao-xuan Wang, Wei-wei Xiao, Hui Chang, Zhi-fan Zeng, Zhen-hai Lu, Xiao-jun Wu, Gong Chen, Zhi-zhong Pan, De-sen Wan, Pei-rong Ding and Yuan-hong Gao

    Citation: Cancer Communications 2018 38:24

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  3. Content type: Review

    Dysregulation of metabolism allows tumor cells to generate needed building blocks as well as to modulate epigenetic marks to support cancer initiation and progression. Cancer-induced metabolic changes alter th...

    Authors: Yi-Ping Wang and Qun-Ying Lei

    Citation: Cancer Communications 2018 38:25

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  4. Content type: Original article

    Average postoperative follow-up intervals vary in patients undergoing hepatocellular carcinoma (HCC) resection because of limited evidence regarding the optimal interval. We aimed to compare the associations o...

    Authors: Wei He, Yun Zheng, Ruhai Zou, Jingxian Shen, Junping Yang, Jiliang Qiu, Qiang Tao, Wenwu Liu, Zhiwen Yang, Yuanping Zhang, Binkui Li and Yunfei Yuan

    Citation: Cancer Communications 2018 38:26

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  5. Content type: Original article

    Few studies have shown nomograms that may predict disease-specific survival (DSS) probability after curative D2 gastrectomy for advanced gastric cancer (AGC), particularly among Chinese patients. This study so...

    Authors: Wei Wang, Zhe Sun, Jing-Yu Deng, Xiao-Long Qi, Xing-Yu Feng, Cheng Fang, Xing-Hua Ma, Zhen-Ning Wang, Han Liang, Hui-Mian Xu and Zhi-Wei Zhou

    Citation: Cancer Communications 2018 38:23

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  6. Content type: Original article

    5-Fluorouracil (5-FU) and capecitabine-associated cardiotoxicity ranging from asymptomatic electrocardiography (ECG) abnormalities to severe myocardial infarction has been reported in a number of studies, but ...

    Authors: Jianjun Peng, Chao Dong, Chang Wang, Weihua Li, Hao Yu, Min Zhang, Qun Zhao, Bo Zhu, Jun Zhang, Wenliang Li, Fenghua Wang, Qiong Wu, Wenhao Zhou, Ying Yuan, Meng Qiu and Gong Chen

    Citation: Cancer Communications 2018 38:22

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  7. Content type: Original article

    Available data in the literature comparing different induction chemotherapy (IC) regimens on locoregionally advanced nasopharyngeal carcinoma (NPC) are scarce. The purpose of the present study was to evaluate ...

    Authors: Guo-Ying Liu, Xing Lv, Yi-Shan Wu, Min-Jie Mao, Yan-Fang Ye, Ya-Hui Yu, Hu Liang, Jing Yang, Liang-Ru Ke, Wen-Ze Qiu, Xin-Jun Huang, Wang-Zhong Li, Xiang Guo, Yan-Qun Xiang and Wei-Xiong Xia

    Citation: Cancer Communications 2018 38:21

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  8. Content type: Original article

    Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations or anaplastic lymphoma kinase (ALK) fusions show dramatic responses to specific tyrosine kinase inhibitors (TKIs)...

    Authors: Yunhua Xu, Feifei Zhang, Xiaoqing Pan, Guan Wang, Lei Zhu, Jie Zhang, Danyi Wen and Shun Lu

    Citation: Cancer Communications 2018 38:19

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  9. Content type: Original article

    Enlarged retropharyngeal lymph nodes (RLNs) are very common in patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy. The most suitable treatment option for enlarged RLNs depends on the patholog...

    Authors: Long-Jun He, Chuanbo Xie, Yin Li, Lin-Na Luo, Ke Pan, Xiao-Yan Gao, Li-Zhi Liu, Jian-Ming Gao, Guang-Yu Luo, Hong-Bo Shan, Ming-Yuan Chen, Chong Zhao, Wei-Jun Fan, Ping Yang, Guo-Liang Xu and Jian-Jun Li

    Citation: Cancer Communications 2018 38:20

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  10. Content type: Original article

    Our previous study demonstrated that aldolase A (ALDOA) is overexpressed in clinical human lung squamous cell carcinoma and that ALDOA promotes epithelial–mesenchymal transition and tumorigenesis. The present ...

    Authors: Hailu Fu, Huijun Gao, Xiaoyu Qi, Lei Zhao, Donghua Wu, Yuxin Bai, Huimin Li, Xuan Liu, Jun Hu and Shujuan Shao

    Citation: Cancer Communications 2018 38:18

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  11. Content type: Review

    Precision medicine has shed new light on the treatment of heterogeneous cancer patients. However, intratumor heterogeneity strongly constrains the clinical benefit of precision medicine. Thus, rethinking thera...

    Authors: Mengying Tong, Ziqian Deng, Xiaolong Zhang, Bin He, Mengying Yang, Wei Cheng and Quentin Liu

    Citation: Cancer Communications 2018 38:17

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  12. Content type: Original article

    Tumor hypoxia is considered an important factor in metastasis and disease relapse. Evofosfamide is a hypoxia-activated prodrug that selectively targets the hypoxic regions of solid tumors. As hypoxia-inducible...

    Authors: Yan Huang, Ying Tian, Yuanyuan Zhao, Cong Xue, Jianhua Zhan, Lin Liu, Xiaobo He and Li Zhang

    Citation: Cancer Communications 2018 38:15

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  13. Content type: Original article

    Pancreatic duct adenocarcinoma (PDAC) remains a major health problem because conventional cancer treatments are relatively ineffective against it. Microarray studies have linked many genes to pancreatic cancer...

    Authors: Jun Li, Wenle Tan, Linna Peng, Jialiang Zhang, Xudong Huang, Qionghua Cui, Jian Zheng, Wen Tan, Chen Wu and Dongxin Lin

    Citation: Cancer Communications 2018 38:13

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  14. Content type: Original article

    The association between type 2 diabetes mellitus (T2DM) and the risk of esophageal cancer remains unclear. The present study aimed to evaluate the impact of T2DM on short-term outcomes and long-term survival i...

    Authors: Wang Yao, Yuqi Meng, Mingjian Lu, Wenzhe Fan, Jinhua Huang, Jiaping Li and Zhihua Zhu

    Citation: Cancer Communications 2018 38:14

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  15. Content type: Review

    Cancer cells often upregulate nutrient transporters to fulfill their increased biosynthetic and bioenergetic needs, and to maintain redox homeostasis. One nutrient transporter frequently overexpressed in human...

    Authors: Pranavi Koppula, Yilei Zhang, Li Zhuang and Boyi Gan

    Citation: Cancer Communications 2018 38:12

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  16. Content type: Original article

    Technical advances in radiotherapy delivery have simultaneously enabled dose escalation and enhanced bladder and rectal sparing. However, the optimal radiation fractionation regimen for localized prostate canc...

    Authors: Bin S. Teh, Gary D. Lewis, Weiyuan Mai, Ramiro Pino, Hiromichi Ishiyama and Edward Brian Butler

    Citation: Cancer Communications 2018 38:11

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  17. Content type: Original article

    Tissue specimens for nasopharyngeal carcinoma (NPC) research are scarce because of sampling difficulties. Previous studies have suggested non-invasive nasopharyngeal brushing as an effective sampling method fo...

    Authors: Pei-Fen Zhang, Xiao-Hui Zheng, Xi-Zhao Li, Tian Tian, Shao-Dan Zhang, Ye-Zhu Hu and Wei-Hua Jia

    Citation: Cancer Communications 2018 38:8

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  18. Content type: Original article

    Esophageal squamous cell carcinoma (ESCC) is the predominant subtype of esophageal carcinoma in China. This study was to develop a staging model to predict outcomes of patients with ESCC.

    Authors: Jin-Cheng Guo, Yang Wu, Yang Chen, Feng Pan, Zhi-Yong Wu, Jia-Sheng Zhang, Jian-Yi Wu, Xiu-E Xu, Jian-Mei Zhao, En-Min Li, Yi Zhao and Li-Yan Xu

    Citation: Cancer Communications 2018 38:4

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  19. Content type: Original article

    The association of circulating inflammation markers with nasopharyngeal carcinoma (NPC) is still largely unclear. This study aimed to comprehensively explore the relationship between circulating cytokine level...

    Authors: Meng-Jie Yang, Jie Guo, Yan-Fang Ye, Sui-Hong Chen, Li-Xia Peng, Chu-Yang Lin, Ting Hu, Shang-Hang Xie, Chuan-Bo Xie, Qi-Hong Huang, Yu-Qiang Lu, Qing Liu, Chao-Nan Qian and Su-Mei Cao

    Citation: Cancer Communications 2018 38:7

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  20. Content type: Original article

    Our previous studies demonstrated that eyes absent homolog 4 (EYA4), a member of the eye development-related EYA family in Drosophila, is frequently methylated and silenced in hepatocellular carcinoma (HCC) speci...

    Authors: Shi-Jing Mo, Xun Hou, Xiao-Yi Hao, Jian-Peng Cai, Xin Liu, Wei Chen, Dong Chen and Xiao-Yu Yin

    Citation: Cancer Communications 2018 38:9

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  21. Content type: Original article

    Surgery and radiotherapy are considered local therapies for small cell lung cancer (SCLC). The present study aimed to select candidates for surgery as local therapy among patients with stage I or II SCLC, base...

    Authors: Kaiqi Jin, Kaixuan Zhang, Feng Zhou, Jie Dai, Peng Zhang and Gening Jiang

    Citation: Cancer Communications 2018 38:5

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