Pathmanathan R, Prasad U, Chandrika G, Sadler R, Flynn K, Raab-Traub N. Undifferentiated, nonkeratinizing, and squamous cell carcinoma of the nasopharynx. Variants of Epstein–Barr virus-infected neoplasia. Am J Pathol. 1995;146(6):1355–67.
CAS
PubMed
PubMed Central
Google Scholar
Chua ML, Wee JT, Hui EP, Chan AT. Nasopharyngeal carcinoma. Lancet. 2016;387(10022):1012–24.
Article
PubMed
Google Scholar
Pak MW, To KF, Leung SF, van Hasselt CA. In vivo diagnosis of nasopharyngeal carcinoma using contact rhinoscopy. Laryngoscope. 2001;111(8):1453–8.
Article
CAS
PubMed
Google Scholar
Zhang LF, Li YH, Xie SH, Ling W, Chen SH, Liu Q, Huang QH, Cao SM. Incidence trend of nasopharyngeal carcinoma from 1987 to 2011 in Sihui County, Guangdong Province, South China: an age-period-cohort analysis. Chin J Cancer. 2015;34(8):350–7.
CAS
PubMed
Google Scholar
Young LS, Dawson CW. Epstein–Barr virus and nasopharyngeal carcinoma. Chin J Cancer. 2014;33(12):581–90.
CAS
PubMed
PubMed Central
Google Scholar
Chan KC. Plasma Epstein–Barr virus DNA as a biomarker for nasopharyngeal carcinoma. Chin J Cancer. 2014;33(12):598–603.
CAS
PubMed
PubMed Central
Google Scholar
Spence T, Bruce J, Yip KW, Liu FF. MicroRNAs in nasopharyngeal carcinoma. Chin Clin Oncol. 2016;5(2):17.
Article
PubMed
Google Scholar
Zheng XH, Lu LX, Li XZ, Jia WH. Quantification of Epstein–Barr virus DNA load in nasopharyngeal brushing samples in the diagnosis of nasopharyngeal carcinoma in southern China. Cancer Sci. 2015;106(9):1196–201.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zheng XH, Lu LX, Cui C, Chen MY, Li XZ, Jia WH. Epstein–Barr virus mir-bart1-5p detection via nasopharyngeal brush sampling is effective for diagnosing nasopharyngeal carcinoma. Oncotarget. 2016;7(4):4972–80.
PubMed
Google Scholar
Ramayanti O, Juwana H, Verkuijlen SA, Adham M, Pegtel MD, Greijer AE, Middeldorp JM. Epstein–Barr virus mRNA profiles and viral DNA methylation status in nasopharyngeal brushings from nasopharyngeal carcinoma patients reflect tumor origin. Int J Cancer. 2017;140(1):149–62.
Article
CAS
PubMed
Google Scholar
Stevens SJ, Verkuijlen SA, Hariwiyanto B, Harijadi, Paramita DK, Fachiroh J, Adham M, Tan IB, Haryana SM, Middeldorp JM. Noninvasive diagnosis of nasopharyngeal carcinoma: nasopharyngeal brushings reveal high Epstein–Barr virus DNA load and carcinoma-specific viral BARF1 mRNA. Int J Cancer. 2006;119(3):608–14.
Article
CAS
PubMed
Google Scholar
Cheung HW, Ching YP, Nicholls JM, Ling MT, Wong YC, Hui N, Cheung A, Tsao SW, Wang Q, Yeun PW, et al. Epigenetic inactivation of CHFR in nasopharyngeal carcinoma through promoter methylation. Mol Carcinog. 2005;43(4):237–45.
Article
CAS
PubMed
Google Scholar
Hutajulu SH, Indrasari SR, Indrawati LP, Harijadi A, Duin S, Haryana SM, Steenbergen RD, Greijer AE, Middeldorp JM. Epigenetic markers for early detection of nasopharyngeal carcinoma in a high risk population. Mol Cancer. 2011;10:48.
Article
CAS
PubMed
PubMed Central
Google Scholar
Low WK. The contact bleeding sign of nasopharyngeal carcinoma. Head Neck. 1997;19(7):617–9.
Article
CAS
PubMed
Google Scholar
Waldron J, Van Hasselt CA, Wong KY. Sensitivity of biopsy using local anesthesia in detecting nasopharyngeal carcinoma. Head Neck. 1992;14(1):24–7.
Article
CAS
PubMed
Google Scholar
Ji MF, Huang QH, Yu X, Liu Z, Li X, Zhang LF, Wang P, Xie SH, Rao HL, Fang F, et al. Evaluation of plasma Epstein–Barr virus DNA load to distinguish nasopharyngeal carcinoma patients from healthy high-risk populations in Southern China. Cancer. 2014;120(9):1353–60.
Article
CAS
PubMed
Google Scholar
Freeman JL, Robinson A, Irish J. Brush biopsy for detection of nasopharyngeal cancer. J Otolaryngol. 2001;30(6):355–6.
Article
CAS
PubMed
Google Scholar
Anker P. Quantitative aspects of plasma/serum DNA in cancer patients. Ann N Y Acad Sci. 2000;906:5–7.
Article
CAS
PubMed
Google Scholar
Adham M, Greijer AE, Verkuijlen SA, Juwana H, Fleig S, Rachmadi L, Malik O, Kurniawan AN, Roezin A, Gondhowiardjo S, et al. Epstein–Barr virus DNA load in nasopharyngeal brushings and whole blood in nasopharyngeal carcinoma patients before and after treatment. Clin Cancer Res. 2013;19(8):2175–86.
Article
CAS
PubMed
Google Scholar
Tune CE, Liavaag PG, Freeman JL, van den Brekel MW, Shpitzer T, Kerrebijn JD, Payne D, Irish JC, Ng R, Cheung RK, et al. Nasopharyngeal brush biopsies and detection of nasopharyngeal cancer in a high-risk population. J Natl Cancer Inst. 1999;91(9):796–800.
Article
CAS
PubMed
Google Scholar
Tong JH, Tsang RK, Lo KW, Woo JK, Kwong J, Chan MW, Chang AR, van Hasselt CA, Huang DP, To KF. Quantitative Epstein–Barr virus DNA analysis and detection of gene promoter hypermethylation in nasopharyngeal (NP) brushing samples from patients with NP carcinoma. Clin Cancer Res. 2002;8(8):2612–9.
CAS
PubMed
Google Scholar
Makitie AA, Reis PP, Zhang T, Chin SF, Gullane P, Siu LL, Kamel-Reid S, Irish J. Epstein–Barr virus DNA measured in nasopharyngeal brushings in patients with nasopharyngeal carcinoma: pilot study. J Otolaryngol. 2004;33(5):299–303.
Article
PubMed
Google Scholar
Yang X, Dai W, Kwong DL, Szeto CY, Wong EH, Ng WT, Lee AW, Ngan RK, Yau CC, Tung SY, et al. Epigenetic markers for noninvasive early detection of nasopharyngeal carcinoma by methylation-sensitive high resolution melting. Int J Cancer. 2015;136(4):E127–35.
Article
CAS
PubMed
Google Scholar
Zhang Z, Sun D, Hutajulu SH, Nawaz I, Van Nguyen D, Huang G, Haryana SM, Middeldorp JM, Ernberg I, Hu LF. Development of a non-invasive method, multiplex methylation specific PCR (MMSP), for early diagnosis of nasopharyngeal carcinoma. PLoS ONE. 2012;7(11):e45908.
Article
CAS
PubMed
PubMed Central
Google Scholar
Jan YJ, Chen SJ, Wang J, Jiang RS. Liquid-based cytology in diagnosing nasopharyngeal carcinoma. Am J Rhinol Allergy. 2009;23(4):422–5.
Article
PubMed
Google Scholar
Chang AR, Liang XM, Chan AT, Chan MK, Teo PM, Johnson PJ. The use of brush cytology and directed biopsies for the detection of nasopharyngeal carcinoma and precursor lesions. Head Neck. 2001;23(8):637–45.
Article
CAS
PubMed
Google Scholar
Yu KH, Lo YM, Tse GM, Chan KC, Chan AB, Chow KC, Ma TK, Vlantis AC, Leung SF, van Hasselt CA, et al. Quantitative analysis of cell-free Epstein–Barr virus DNA in plasma of patients with nonnasopharyngeal head and neck carcinomas. Clin Cancer Res. 2004;10(5):1726–32.
Article
CAS
PubMed
Google Scholar
Sheen TS, Ko JY, Chang YL, Chang YS, Huang YT, Chang Y, Tsai CH, Hsu MM. Nasopharyngeal swab and PCR for the screening of nasopharyngeal carcinoma in the endemic area: a good supplement to the serologic screening. Head Neck. 1998;20(8):732–8.
Article
CAS
PubMed
Google Scholar
Thorley-Lawson DA. Epstein–Barr virus: exploiting the immune system. Nat Rev Immunol. 2001;1(1):75–82.
Article
CAS
PubMed
Google Scholar
Laichalk LL, Hochberg D, Babcock GJ, Freeman RB, Thorley-Lawson DA. The dispersal of mucosal memory B cells: evidence from persistent EBV infection. Immunity. 2002;16(5):745–54.
Article
CAS
PubMed
Google Scholar
Poh SS, Chua ML, Wee JT. Carcinogenesis of nasopharyngeal carcinoma: an alternate hypothetical mechanism. Chin J Cancer. 2016;35:9.
Article
PubMed
PubMed Central
Google Scholar
Li L, Zhang Y, Fan Y, Sun K, Su X, Du Z, Tsao SW, Loh TK, Sun H, Chan AT, et al. Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes. Epigenomics. 2015;7(2):155–73.
Article
PubMed
Google Scholar
Ng RH, Ngan R, Wei WI, Gullane PJ, Phillips J. Trans-oral brush biopsies and quantitative PCR for EBV DNA detection and screening of nasopharyngeal carcinoma. Otolaryngol Head Neck Surg. 2014;150(4):602–9.
Article
PubMed
Google Scholar
Chen YP, Zhao BC, Chen C, Shen LJ, Gao J, Mai ZY, Chen MK, Chen G, Yan F, Liu S, et al. Pretreatment platelet count improves the prognostic performance of the TNM staging system and aids in planning therapeutic regimens for nasopharyngeal carcinoma: a single-institutional study of 2,626 patients. Chin J Cancer. 2015;34(3):137–46.
PubMed
Google Scholar