Riemenschneider MJ, Perry A, Reifenberger G. Histological classification and molecular genetics of meningiomas. Lancet Neurol. 2006;5(12):1045–54. https://doi.org/10.1016/S1474-4422(06)70625-1.
Article
CAS
PubMed
Google Scholar
Ostrom QT, Gittleman H, Xu J, Kromer C, Wolinsky Y, Kruchko C, et al. CBTRUS Statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2009–2013. Neuro Oncol. 2016;18(suppl_5):v1–75. https://doi.org/10.1093/neuonc/now207.
Article
PubMed
Google Scholar
Jiang T, Tang GF, Lin Y, Peng XX, Zhang X, Zhai XW, et al. Prevalence estimates for primary brain tumors in China: a multi-center cross-sectional study. Chin Med J (Engl). 2011;124(17):2578–83.
Google Scholar
Schweitzer T, Vince GH, Herbold C, Roosen K, Tonn JC. Extraneural metastases of primary brain tumors. J Neurooncol. 2001;53(2):107–14.
Article
CAS
PubMed
Google Scholar
Adlakha A, Rao K, Adlakha H, Perry A, Crotty TB, Scheithauer BW, et al. Meningioma metastatic to the lung. Mayo Clin Proc. 1999;74(11):1129–33. https://doi.org/10.4065/74.11.1129.
Article
CAS
PubMed
Google Scholar
Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, et al. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nat Genet. 2013;45(3):285–9. https://doi.org/10.1038/ng.2526.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bi WL, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ, Agarwalla PK, et al. Genomic landscape of high-grade meningiomas. NPJ Genom Med. 2017;2(1):15. https://doi.org/10.1038/s41525-017-0014-7.
Article
PubMed
PubMed Central
Google Scholar
Tang M, Wei H, Han L, Deng J, Wang Y, Yang M, et al. Whole-genome sequencing identifies new genetic alterations in meningiomas. Oncotarget. 2017;8(10):17070–80. https://doi.org/10.18632/oncotarget.15043.
Article
PubMed
PubMed Central
Google Scholar
McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, Kernytsky A, et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 2010;20(9):1297–303. https://doi.org/10.1101/gr.107524.110.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gonzalez-Perez A, Perez-Llamas C, Deu-Pons J, Tamborero D, Schroeder MP, Jene-Sanz A, et al. IntOGen-mutations identifies cancer drivers across tumor types. Nat Methods. 2013;10(11):1081–2. https://doi.org/10.1038/nmeth.2642.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kalamarides M, Niwa-Kawakita M, Leblois H, Abramowski V, Perricaudet M, Janin A, et al. Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse. Genes Dev. 2002;16(9):1060–5. https://doi.org/10.1101/gad.226302.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zhang N, Bai H, David KK, Dong J, Zheng Y, Cai J, et al. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Dev Cell. 2010;19(1):27–38. https://doi.org/10.1016/j.devcel.2010.06.015.
Article
CAS
PubMed
PubMed Central
Google Scholar
Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, et al. Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior. Cancer Res. 2007;67(22):10899–909. https://doi.org/10.1158/0008-5472.CAN-07-2837.
Article
CAS
PubMed
Google Scholar
Buchert M, Darido C, Lagerqvist E, Sedello A, Cazevieille C, Buchholz F, et al. The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1. Gastroenterology. 2009;137(1):156–64. https://doi.org/10.1053/j.gastro.2009.03.037.
Article
CAS
PubMed
Google Scholar
Sourisseau T, Georgiadis A, Tsapara A, Ali RR, Pestell R, Matter K, et al. Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA. Mol Cell Biol. 2006;26(6):2387–98. https://doi.org/10.1128/MCB.26.6.2387-2398.2006.
Article
CAS
PubMed
PubMed Central
Google Scholar
Nishitani H, Lygerou Z, Nishimoto T, Nurse P. The Cdt1 protein is required to license DNA for replication in fission yeast. Nature. 2000;404(6778):625–8. https://doi.org/10.1038/35007110.
Article
CAS
PubMed
Google Scholar
Fagerberg L, Hallstrom BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, et al. Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteomics. 2014;13(2):397–406. https://doi.org/10.1074/mcp.M113.035600.
Article
CAS
PubMed
Google Scholar
Ioannidis NM, Rothstein JH, Pejaver V, Middha S, McDonnell SK, Baheti S, et al. REVEL: an ensemble method for predicting the pathogenicity of rare missense variants. Am J Hum Genet. 2016;99(4):877–85. https://doi.org/10.1016/j.ajhg.2016.08.016.
Article
CAS
PubMed
PubMed Central
Google Scholar
Jagadeesh KA, Wenger AM, Berger MJ, Guturu H, Stenson PD, Cooper DN, et al. M-CAP eliminates a majority of variants of uncertain significance in clinical exomes at high sensitivity. Nat Genet. 2016;48(12):1581–6. https://doi.org/10.1038/ng.3703.
Article
CAS
PubMed
Google Scholar
Saunders CT, Wong WS, Swamy S, Becq J, Murray LJ, Cheetham RK. Strelka: accurate somatic small-variant calling from sequenced tumor-normal sample pairs. Bioinformatics. 2012;28(14):1811–7. https://doi.org/10.1093/bioinformatics/bts271.
Article
CAS
PubMed
Google Scholar
Koboldt DC, Zhang Q, Larson DE, Shen D, McLellan MD, Lin L, et al. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res. 2012;22(3):568–76. https://doi.org/10.1101/gr.129684.111.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature. 2010;467(7319):1114–7. https://doi.org/10.1038/nature09515.
Article
CAS
PubMed
PubMed Central
Google Scholar
Urbschat S, Rahnenfuhrer J, Henn W, Feiden W, Wemmert S, Linsler S, et al. Clonal cytogenetic progression within intratumorally heterogeneous meningiomas predicts tumor recurrence. Int J Oncol. 2011;39(6):1601–8. https://doi.org/10.3892/ijo.2011.1199.
PubMed
Google Scholar
Miller CA, White BS, Dees ND, Griffith M, Welch JS, Griffith OL, et al. SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution. PLoS Comput Biol. 2014;10(8):e1003665. https://doi.org/10.1371/journal.pcbi.1003665.
Article
PubMed
PubMed Central
Google Scholar
Volovitz I, Marmor Y, Azulay M, Machlenkin A, Goldberger O, Mor F, et al. Split immunity: immune inhibition of rat gliomas by subcutaneous exposure to unmodified live tumor cells. J Immunol. 2011;187(10):5452–62. https://doi.org/10.4049/jimmunol.1003946.
Article
CAS
PubMed
Google Scholar
DuPage M, Mazumdar C, Schmidt LM, Cheung AF, Jacks T. Expression of tumour-specific antigens underlies cancer immunoediting. Nature. 2012;482(7385):405–9. https://doi.org/10.1038/nature10803.
Article
CAS
PubMed
PubMed Central
Google Scholar
Szolek A, Schubert B, Mohr C, Sturm M, Feldhahn M, Kohlbacher O. OptiType: precision HLA typing from next-generation sequencing data. Bioinformatics. 2014;30(23):3310–6. https://doi.org/10.1093/bioinformatics/btu548.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kawaguchi S, Higasa K, Shimizu M, Yamada R, Matsuda F. HLA-HD: an accurate HLA typing algorithm for next-generation sequencing data. Hum Mutat. 2017;38(7):788–97. https://doi.org/10.1002/humu.23230.
Article
CAS
PubMed
Google Scholar
Kaminski JM, Movsas B, King E, Yang C, Kronz JD, Alli PM, et al. Metastatic meningioma to the lung with multiple pleural metastases. Am J Clin Oncol. 2001;24(6):579–82.
Article
CAS
PubMed
Google Scholar
Beauchesne P. Extra-neural metastases of malignant gliomas: myth or reality? Cancers (Basel). 2011;3(1):461–77. https://doi.org/10.3390/cancers3010461.
Article
PubMed
PubMed Central
Google Scholar
Subramanian A, Harris A, Piggott K, Shieff C, Bradford R. Metastasis to and from the central nervous system—the ‘relatively protected site’. Lancet Oncol. 2002;3(8):498–507.
Article
CAS
PubMed
Google Scholar
Muller C, Holtschmidt J, Auer M, Heitzer E, Lamszus K, Schulte A, et al. Hematogenous dissemination of glioblastoma multiforme. Sci Transl Med. 2014;6(247):247ra101. https://doi.org/10.1126/scitranslmed.3009095.
Article
PubMed
Google Scholar
Lau LW, Cua R, Keough MB, Haylock-Jacobs S, Yong VW. Pathophysiology of the brain extracellular matrix: a new target for remyelination. Nat Rev Neurosci. 2013;14(10):722–9. https://doi.org/10.1038/nrn3550.
Article
CAS
PubMed
Google Scholar
Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523(7560):337–41. https://doi.org/10.1038/nature14432.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mourad PD, Farrell L, Stamps LD, Chicoine MR, Silbergeld DL. Why are systemic glioblastoma metastases rare? Systemic and cerebral growth of mouse glioblastoma. Surg Neurol. 2005;63(6):511–9. https://doi.org/10.1016/j.surneu.2004.08.062.
Article
PubMed
Google Scholar
Frydrychowicz C, Holland H, Hantmann H, Gradistanac T, Hoffmann KT, Mueller W, et al. Two cases of atypical meningioma with pulmonary metastases: a comparative cytogenetic analysis of chromosomes 1p and 22 and a review of the literature. Neuropathology. 2015;35(2):175–83. https://doi.org/10.1111/neup.12177.
Article
PubMed
Google Scholar
Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, et al. Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets. Cancer Discov. 2015;5(11):1164–77. https://doi.org/10.1158/2159-8290.CD-15-0369.
Article
CAS
PubMed
PubMed Central
Google Scholar
Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y, et al. C11orf95-RELA fusions drive oncogenic NF-kappaB signalling in ependymoma. Nature. 2014;506(7489):451–5. https://doi.org/10.1038/nature13109.
Article
CAS
PubMed
PubMed Central
Google Scholar
Brannon AR, Vakiani E, Sylvester BE, Scott SN, McDermott G, Shah RH, et al. Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions. Genome Biol. 2014;15(8):454. https://doi.org/10.1186/s13059-014-0454-7.
Article
PubMed
PubMed Central
Google Scholar