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Table 2 Metrics of whole-exome sequencing (WES) analysis of the specimens from the proband and his relatives entering into the present study

From: Whole exome sequencing and single nucleotide polymorphism array analyses to identify germline alterations in genes associated with testosterone metabolism in a patient with androgen insensitivity syndrome and early-onset colorectal cancer

Metric III.2 Proband’s blood sample III.2 Proband’s normal colon tissue III.2 Proband’s CRC tissue II.1 Father’s blood sample II.2 Mother’s blood sample II.3 Aunt’s blood sample III.3 Cousin’s blood sample
Total reads 801,798,464 631,026,099 631,377,353 633,336,574 98,744,957 98,744,957 397,006,863
Mapped reads 481,096,544 350,445,297 434,605,056 330,283,413 66,488,953 73,450,351 243,481,688
On-target reads 266,671,188 185,116,968 217,278,894 237,886,825 47,482,595 65,141,598 142,790,642
% mapped reads 60.0 55.5 68.8 52.2 26.8 74.4 61.3
% on-target reads 55.4 52.8 50.0 72.0 71.4 88.7 58.7
% covered target reads 96.7 92.6 91.6 94.9 86.7 88.6 94.9
Average depth coverage 288.6 200.3 235.1 257.4 51.4 70.5 154.5