From: Carcinogenic effects of circadian disruption: an epigenetic viewpoint
Cancer type | Involved gene(s) | Reference(s) |
---|---|---|
Breast cancer | NPAS2, CLOCK, CRY2, TIMELESS, PER1, PER2, CRY1, and BMAL1 | |
Chronic myeloid leukemia (CML) | CRY1, CRY2, PER1, PER2, PER3, CKIε, and BMAL1 | |
Chronic lymphocytic leukemia (CLL) | PER1, PER2, BMAL1, Wee1, Cyclin D1, and Myc | [30] |
Ovarian cancer | BMAL1 | [44] |
Colorectal cancer (CRC) | BMAL1 | [47] |
Prostate cancer | PER1, PER2, PER3, CKIε, CRY1, CRY2, BMAL1, CLOCK, and NPAS2 | |
Non–small cell lung cancer (NSCLC) | PER1 | [51] |
Gastric cancer | PER2 and CRY1 | [29] |
Head and neck squamous cell carcinoma (HNSCC) | PER1, PER2, PER3, CRY1, CRY2, CKIε, BMAL1, and TIM | [61] |