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Table 1 Differential cytokine and receptor expression of cytokine-induced killer (CIK) cells upon stimulation by tumor cells

From: Cytokine-induced killer (CIK) cells: from basic research to clinical translation

Cytokine/receptor Secretion/expression status
With stimulus Without stimulus
IL-2 + +
IFN-γ + +
TNF-α + +
GM-CSF + -
IL-4 + -
IL-2R + +
IL-4R + +
IL-10R - +
IL-12R + -
IL-15R + -
  1. IL-2, interleukin 2; IL-4, interleukin 4; IFN-γ, interferon γ; TNF-α, tumor necrosis factor α; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-2R, interleukin 2 receptor; IL-4R, interleukin 4 receptor; IL-10R, interleukin 10 receptor; IL-12R, interleukin 12 receptor; IL-15R, interleukin 15 receptor. “+” indicates secreted or expressed; “-” indicates not secreted or expressed.