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Table 2. Analysis of potential predictors of time to treatment response among 25 patients (39 tumors) with hepatocellular carcinoma treated with radiotherapy

From: Optimal follow-up duration for evaluating objective response to radiotherapy in patients with hepatocellular carcinoma: a retrospective study

Variable Cases Median time to objective response (months) P value
Univariate Multivariate
Age (years)    0.001 0.005
  < 60 16 3.8   
60 23 5.0   
Sex    0.081 0.342
  Men 27 4.0   
  Women 12 5.0   
ECOG performance status    0.391 0.785
  0 18 3.8   
  1–2 21 5.0   
Tumor size (cm)    0.489 0.380
  < 1.7 18 4.5   
1.7 21 3.9   
GTV (cm3)    0.195 0.847
  < 7 20 4.9   
7 19 3.8   
Pre-radiotherapy AFP concentration (IU/mL)    0.270 0.625
  < 25 20 4.0   
25 19 4.5   
AFP concentration change    0.003 0.047
  < 1 19 4.0   
1 20 6.1   
Total radiotherapy dose (Gy10)    0.586 0.666
  < 67 18 4.5   
67 21 3.9   
Daily radiotherapy dose (Gy)    0.672 0.928
  < 2.5 13 3.0   
2.5 26 4.9   
Pre-radiotherapy TACE    0.178 0.650
  Yes 23 3.8   
  No 16 4.9   
  1. Abbreviations as in Table 1.