Survival analysis of children with stage II testicular malignant germ cell tumors treated with surgery or surgery combined with adjuvant chemotherapy

Table 2. Clinical characteristics and treatment of 16 children with relapse and metastasis

Number of patient	Age (months)	Preoperative AFP level (ng/mL)	AFP level at relapse or metastasis (ng/mL)	Sites of relapse	Site of metastasis	Treatment after relapse and metastasis	Cycles of C	Prognosis
1	30	968	115	-	-	C	4	A
2	24	11,000	808	LSC	-	S + C	4	A
3	27	25,000	2,054	LT	PLN, L	S + C	7	A
4	35	13,000	1,199	RS	PILN, DALN	C + S	2	A
5	36	12,000	NA	-	AC	C	1	D*
6	18	3,309	> 35,350	-	AC	C + S + C	6	A
7	48	1,000	800	-	AC	C	10	A
8	36	2,390	602	-	RLN	C	6	A
9	31	40,600	> 121,000	-	APC	C + S	4	D
10	20	1,000	> 121,000	-	RLN	C	6	A
11	21	8,914	56,367	-	AC, LILN MLN	C	6	A
12	11	3,675	75	-	L	C	6	A
13	48	10,080	36	-	L	C	6	A
14	24	25,620	2,455	-	L, P	C	6	A
15	18	30,000	25,808	-	L, HLN, MLN	C	8	A
16	24	30,600	3,533	-	L, HLN, MLN, RLN	C	6	A

LSC, left spermatic cord; LT, left testis; RS, right scrotal; PLN, para-aortic lymph node; L, lung; PILN, pairs of inguinal lymph nodes; DALN, double axillary lymph nodes; AC, abdominal cavity; RLN, retroperitoneal lymph node; APC, abdomen and pelvic cavity; LILN, left inguinal lymph node; MLN, mediastinal lymph node; P, pleura; HLN, hilar lymph node; C, chemotherapy; S, surgery; A, alive; D, dead. NA, not available.
D*: The patient’s parents refused further treatment after one cycle of chemotherapy and then the child died due to the tumor 3 months later.

ISSN: 2523-3548