Skip to main content

Advertisement

Table 2. Clinical characteristics and treatment of 16 children with relapse and metastasis

From: Survival analysis of children with stage II testicular malignant germ cell tumors treated with surgery or surgery combined with adjuvant chemotherapy

Number of patient Age (months) Preoperative AFP level (ng/mL) AFP level at relapse or metastasis (ng/mL) Sites of relapse Site of metastasis Treatment after relapse and metastasis Cycles of C Prognosis
1 30 968 115 - - C 4 A
2 24 11,000 808 LSC - S + C 4 A
3 27 25,000 2,054 LT PLN, L S + C 7 A
4 35 13,000 1,199 RS PILN, DALN C + S 2 A
5 36 12,000 NA - AC C 1 D*
6 18 3,309 > 35,350 - AC C + S + C 6 A
7 48 1,000 800 - AC C 10 A
8 36 2,390 602 - RLN C 6 A
9 31 40,600 > 121,000 - APC C + S 4 D
10 20 1,000 > 121,000 - RLN C 6 A
11 21 8,914 56,367 - AC, LILN MLN C 6 A
12 11 3,675 75 - L C 6 A
13 48 10,080 36 - L C 6 A
14 24 25,620 2,455 - L, P C 6 A
15 18 30,000 25,808 - L, HLN, MLN C 8 A
16 24 30,600 3,533 - L, HLN, MLN, RLN C 6 A
  1. LSC, left spermatic cord; LT, left testis; RS, right scrotal; PLN, para-aortic lymph node; L, lung; PILN, pairs of inguinal lymph nodes; DALN, double axillary lymph nodes; AC, abdominal cavity; RLN, retroperitoneal lymph node; APC, abdomen and pelvic cavity; LILN, left inguinal lymph node; MLN, mediastinal lymph node; P, pleura; HLN, hilar lymph node; C, chemotherapy; S, surgery; A, alive; D, dead. NA, not available.
  2. D*: The patient’s parents refused further treatment after one cycle of chemotherapy and then the child died due to the tumor 3 months later.