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Table 4 Cell cycle alteration after bortezomib treatment

From: Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1–Survivin axis

Cell line

Group

Percentage of cells in different cell cycle phases (%)

Phase G1

Phase S

Phase G2

U251

Control

43.87 ± 2.77

38.12 ± 3.50

18.01 ± 2.23

10 nmol/L

54.44 ± 6.32

33.42 ± 3.22

12.15 ± 1.22

20 nmol/L

70.83 ± 7.54

22.42 ± 2.52

6.74 ± 2.10

U87

Control

45.97 ± 2.99

37.06 ± 2.52

16.97 ± 1.88

10 nmol/L

53.1 ± 64.3

32.41 ± 2.21

14.43 ± 1.90

20 nmol/L

76.35 ± 6.54

14.89 ± 1.50

8.76 ± 2.22