Skip to main content

Table 2 Time schedule of this study

From: Neoadjuvant stereotactic radiosurgery for intracerebral metastases of solid tumors (NepoMUC): a phase I dose escalation trial

TimepointEnrollmentTreatmentFollow-up (months)Close-out (months)
Day 0Preoperative RT
Day 1
Resection
Days 2–7
Postoperative Days 1–2Postoperative Days 3–51,536912
Enrollment
 Eligibility screeningX         
 Informed consentX         
 Study visitXX  XXXXXX
 Planning CTWithin 1–7 days after enrollment         
 Planning MRIWithin 1–7 days after enrollment         
Interventions
 Neoadjuvant SRS X        
 Resection  X       
Assessments
 MRIX  X XXXXX
 Clinical-neurological examinationXXXXXXXXXX
 Minimental state examinationX    XXXXX
 Health-related QoLX   XXXXXX
 ToxicitiesX   XXXXXX
 Adverse events Continuous assessmentXXXXX
  1. This table of study schedule is based on the the SPIRIT© checklist, minor changes were made for adaption to the NepoMUC protocol
  2. CT computer tomography, MRI magnetic resonance tomography, SRS stereotactic radiosurgery