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Table 2 Inquiry of quality of life using the QLQ-C30, QLQ-H&N35

From: Minimally invasive surgery alone compared with intensity-modulated radiotherapy for primary stage I nasopharyngeal carcinoma

EORTC scale score

ENPG (N = 10)

IMRT (N = 220)

P

Mean ± SD

Mean ± SD

QLQ-C30

 Global health status

99.2 ± 2.6

96.5 ± 11.5

0.638

Functional scales

 Physical functioning

98.7 ± 2.8

96.6 ± 14.4

0.738

 Role functioning

100

97.4 ± 14.9

0.568

 Emotional functioning

99.2 ± 2.6

98.5 ± 7.0

0.643

 Cognitive functioning

96.7 ± 7.0

97.7 ± 8.3

0.336

 Social functioning

100

97.4 ± 14.5

0.540

Symptom scales

 Fatigue

1.1 ± 3.5

2.2 ± 12.0

0.402

 Nausea and vomiting

0

0.2 ± 2.5

0.763

 Pain

0

2.3 ± 10.2

0.449

 Dyspnea

0

0.6 ± 4.5

0.668

 Insomnia

0

1.7 ± 9.1

0.540

 Appetite loss

0

8.3 ± 15.8

0.086

 Constipation

0

0.3 ± 3.2

0.763

 Diarrhea

0

0.2 ± 2.2

0.831

 Financial difficulties

0

2.4 ± 14.4

0.568

QLQ-H & N35

 Pain

0

4.1 ± 7.4

0.042

 Swallowing

0

11.4 ± 18.5

0.016

 Senses problems

3.3 ± 10.5

2.3 ± 7.8

0.884

 Speech problems

0

1.7 ± 5.6

0.307

 Social eating

1.7 ± 3.5

4.3 ± 9.6

0.431

 Social contact

0

1.2 ± 7.0

0.568

 Sexuality

0

2.9 ± 12.4

0.394

 Teeth

3.3 ± 10.5

5.5 ± 15.0

0.749

 Opening mouth

0

5.5 ± 12.4

0.165

 Dry mouth

3.3 ± 10.5

34.4 ± 25.8

< 0.001

 Sticky saliva

3.3 ± 10.5

32.6 ± 23.3

< 0.001

 Coughing

0

0.8 ± 5.0

0.631

 Felt ill

0

3.3 ± 17.1

0.515

 Pain killers

0

2.7 ± 18.9

0.631

 Nutritional supplements

0

3.6 ± 23.1

0.598

 Feeding tube

0

0.5 ± 6.7

0.831

 Weight loss

10.0 ± 31.6

10.0 ± 45.7

0.572

 Weight gain

0

2.7 ± 16.3

0.597

  1. Italic values indicate significance of P value (P < 0.05)
  2. EORTC the European Organization for Research and Treatment of Cancer, QLQ-C30 Quality-of-Life Questionnaire–Core 30 general, QLQ-H&N35 head and Neck–specific questionnaires, ENPG endoscopic nasopharyngectomy, IMRT intensity-modulated radiotherapy, SD standard deviation