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Table 3 Comparison of postoperative outcomes between PDAC patients in the OPD and LPD groups

From: Laparoscopic versus open pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: a propensity score matching analysis

Characteristic

Original cohort

P

Matched cohort

P

OPD group

(n = 230)

LPD group

(n = 79)

OPD group

(n = 93)

LPD group

(n = 55)

POPF [cases (%)]

86 (37.4)

20 (25.3)

0.051

33 (35.5)

13 (23.6)

0.132

 Biochemical leak

74 (32.2)

13 (16.5)

0.007

28 (30.1)

9 (16.4)

0.062

 Grade B/C

12 (5.2)

7 (8.9)

0.373

5 (5.4)

4 (7.3)

0.912

DGE [cases (%)]

66 (28.7)

1 (1.3)

< 0.001

34 (36.6)

1 (1.8)

< 0.001

 Grade A

27 (11.7)

0 (0.0)

0.001

13 (14.0)

0 (0.0)

0.009

 Grade B/C

39 (17.0)

1 (1.3)

< 0.001

21 (22.6)

1 (1.8)

0.001

PPH [cases (%)]

14 (6.1)

6 (7.6)

0.638

10 (10.8)

4 (7.3)

0.485

 Grade A

5 (2.2)

1 (1.3)

0.974

4 (4.3)

0 (0.0)

0.301

 Grade B/C

9 (3.9)

5 (6.3)

0.564

6 (6.5)

4 (7.3)

1.000

BL [cases (%)]

15 (6.5)

6 (7.6)

0.744

5 (5.4)

6 (10.9)

0.360

 Grade A

5 (2.2)

0 (0.0)

0.421

2 (2.2)

0 (0.0)

0.530a

 Grade B/C

10 (4.3)

6 (7.6)

0.407

3 (3.2)

6 (10.9)

0.125

Intra-abdominal infection [cases (%)]

21 (9.1)

4 (5.1)

0.253

12 (12.9)

2 (3.6)

0.063

Wound infection [cases (%)]

3 (1.3)

4 (5.1)

0.134

0 (0.0)

2 (3.6)

0.137a

Other complications [cases (%)]

24 (10.4)

8 (10.1)

0.938

11 (11.8)

6 (10.9)

0.865

Overall complications [cases (%)]

151 (65.7)

39 (49.4)

0.010

66 (71.0)

27 (49.1)

0.008

 Clavien I–II

133 (57.8)

30 (38.0)

0.002

53 (57.0)

21 (38.2)

0.027

 Clavien III–V

18 (7.8)

9 (11.4)

0.333

13 (14.0)

6 (10.9)

0.590

DSA [cases (%)]

7 (3.0)

5 (6.3)

0.334

5 (5.4)

4 (7.3)

0.912

Reoperation [cases (%)]

3 (1.3)

5 (6.3)

0.044

1 (1.1)

2 (3.6)

0.642

In-hospital mortality [cases (%)]

2 (0.9)

1 (1.3)

1.000a

2 (2.2)

0 (0.0)

0.530a

Readmission [cases (%)]

32 (13.9)

8 (10.1)

0.387

14 (15.1)

6 (10.9)

0.476

Postoperative length of stay [days, median (IQR)]

13.0 (10.0–19.0)

12.0 (10.0–18.0)

0.947

14.0 (10.0–20.0)

13.0 (11.0–20.0)

0.986

Time to adjuvant chemotherapy [days, median (IQR)]

44.0 (33.8–63.0)

39.0 (32.0–77.0)

0.616

43.5 (32.8–57.3)

39.0 (32.5–81.0)

0.935

  1. PDAC pancreatic ductal adenocarcinoma, OPD open pancreaticoduodenectomy, LPD laparoscopic pancreaticoduodenectomy, POPF postoperative pancreatic fistula, DGE delayed gastric emptying, PPH post-pancreatectomy hemorrhage, BL bile leakage, DSA digital subtraction angiography, IQR interquartile range
  2. aFisher’s exact test
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