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Table 3 Analysis of the 5-year overall survival rates of patients using the 8th AJCC pN classification stratified into Limited (< 16 eLNs) and Adequate (≥ 16 eLNs) eLN cohorts

From: A homogenized approach to classify advanced gastric cancer patients with limited and adequate number of pathologically examined lymph nodes

Nodal classification Limited eLN cohort Adequate eLN cohort P value (Limited vs. Adequate eLN cohort) Combined eLN cohort
Number [cases (%)] 5-year OS (%) Number [cases (%)] 5-year OS (%) Number [cases (%)] 5-year OS (%)
8th AJCC pN
 N0 271 (34.1) 76.4 382 (25.3) 87.5 < 0.001 653 (28.3) 82.7
 N1 207 (26.1) 57.1 227 (15.0) 73.4 < 0.001 434 (18.8) 65.2
 N2 209 (26.3) 36.3 282 (18.7) 60.8 < 0.001 491 (21.3) 49.4
 N3a 107 (13.5) 19.2 382 (25.3) 43.0 < 0.001 489 (21.2) 37.8
 N3b    237 (15.7) 24.8   237 (10.3) 24.8
pN′
 N′0    382 (25.3) 87.5   382 (16.6) 87.5
 N′1 271 (34.1) 76.4 227 (15.0) 73.4 0.853 498 (21.6) 75.1
 N′2 207 (26.1) 57.1 282 (18.7) 60.8 0.476 489 (21.2) 59.1
 N′3a 209 (26.3) 36.3 382 (25.3) 43.0 0.114 591 (25.7) 40.4
 N′3b 107 (13.5) 19.2 237 (15.7) 24.8 0.230 344 (14.9) 23.1
8th AJCC pTNM
 IB 57 (7.2) 91.6 105 (7.0) 96.9 0.136 162 (7.0) 94.8
 IIA 81 (10.2) 78.5 121 (8.0) 90.4 0.169 202 (8.8) 85.3
 IIB 195 (24.6) 72.4 281 (18.6) 77.7 0.038 476 (20.7) 75.5
 IIIA 305 (38.4) 42.9 369 (24.4) 66.1 < 0.001 674 (29.3) 54.7
 IIIB 137 (17.3) 25.4 364 (24.1) 43.9 < 0.001 501 (21.7) 38.8
 IIIC 19 (2.4) 8.4 270 (17.9) 24.3 0.016 289 (12.5) 23.2
pTN′M
 IB′    105 (7.0) 96.9   105 (4.6) 96.9
 IIA′ 57 (7.2) 91.6 121 (8.0) 90.4 0.677 178 (7.7) 90.7
 IIB′ 81 (10.2) 78.5 281 (18.6) 77.7 0.995 362 (15.7) 77.8
 IIIA′ 316 (39.8) 63.1 369 (24.4) 66.1 0.325 685 (29.7) 64.6
 IIIB′ 205 (25.8) 39.3 364 (24.1) 43.9 0.197 569 (24.7) 42.2
 IIIC′ 135 (17.0) 18.8 270 (17.9) 24.3 0.218 405 (17.6) 22.4
  1. eLNs pathologically examined lymph nodes, OS overall survival rate, AJCC American Joint Committee on Cancer, pN pathologically examined nodal classification, N′ pathologically examined modified nodal classification, pTNM pathological tumor-node-metastasis classification, TNM pathological tumor-modified node-metastasis classification