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Fig. 1 | Cancer Communications

Fig. 1

From: Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis

Fig. 1

BaF3/ITD-R and MV4-11-R cells are highly resistant to sorafenib. a BaF3/ITD, BaF3/ITD-R, MV4-11 and MV4-11-R cells were treated with the indicated concentrations of sorafenib for 48 h and subjected to an Annexin-V/PI assay. The percentage values indicate the total cell death populations. b BaF3/ITD, BaF3/ITD-R, MV4-11 and MV4-11-R cells were treated with various concentrations of sorafenib for 72 h and subjected to an MTS assay. The numbers on the curves indicate the IC50 of sorafenib in each cell line. PI propidium iodide

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