Fig. 1From: Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysisBaF3/ITD-R and MV4-11-R cells are highly resistant to sorafenib. a BaF3/ITD, BaF3/ITD-R, MV4-11 and MV4-11-R cells were treated with the indicated concentrations of sorafenib for 48 h and subjected to an Annexin-V/PI assay. The percentage values indicate the total cell death populations. b BaF3/ITD, BaF3/ITD-R, MV4-11 and MV4-11-R cells were treated with various concentrations of sorafenib for 72 h and subjected to an MTS assay. The numbers on the curves indicate the IC50 of sorafenib in each cell line. PI propidium iodideBack to article page