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Table 1 Characteristics of 82 NPC patients with residual cervical lymphadenopathy
| Characteristic | Tumor cells in cervical lymph nodes [cases (%)] | P value | |
|---|---|---|---|
| Presence | Absence | ||
| Total | 68 | 14 | |
| Sex | 0.045¶ | ||
| Male | 52 (76.5) | 7 (50.0) | |
| Female | 16 (23.5) | 7 (50.0) | |
| Pathological type | 0.133& | ||
| WHO type II | 2 (2.9) | 2 (14.3) | |
| WHO type III | 66 (97.1) | 12 (85.7) | |
| T stagea | 0.334# | ||
| T1 | 0 (0) | 1 (7.1) | |
| T2 | 24 (35.3) | 4 (28.6) | |
| T3 | 35 (51.5) | 7 (50.0) | |
| T4 | 9 (13.2) | 2 (14.3) | |
| N stagea | 0.974# | ||
| N1 | 13 (19.1) | 3 (21.4) | |
| N2 | 34 (50.0) | 7 (50.0) | |
| N3 | 21 (30.9) | 4 (28.6) | |
| Clinical stagea | 0.179¶ | ||
| II | 7 (10.3) | 4 (28.6) | |
| III | 34 (50.0) | 5 (35.7) | |
| IV | 27 (39.7) | 5 (35.7) | |
| EBV DNA before treatment (copies/mL) | 0.252¶ | ||
| ≤ 4000 | 23 (33.8) | 7 (50.0) | |
| > 4000 | 45 (66.2) | 7 (50.0) | |
| EBV DNA before surgery (copy/mL) < 0.001# | |||
| 0 | 32 (47.1) | 14 (100) | |
| > 0 | 36 (52.9) | 0 (0.0) | |
| VCA-IgA | 0.988¶ | ||
| < 1:320 | 29 (42.6) | 6 (42.9) | |
| ≥ 1:320 | 39 (57.4) | 8 (57.1) | |
| EA-IgA | 0.196¶ | ||
| < 1:20 | 27 (39.7) | 3 (21.4) | |
| ≥ 1:20 | 41 (60.3) | 11 (78.6) | |
| Size of lymph node 0.747¶ | |||
| < 3 cm | 42 (61.8) | 8 (57.1) | |
| ≥ 3 cm | 26 (38.2) | 6 (42.9) | |
| Lymph node invasion 1.000# | |||
| Yes | 4 (5.9) | 0 (0.0) | |
| No | 64 (94.1) | 14 (100) | |
| Lymph node necrosis 0.865¶ | |||
| Yes | 16 (23.5) | 3 (21.4) | |
| No | 52 (76.5) | 11 (78.6) | |
| Treatment for cervical lymphadenopathy | 0.285# | ||
| Surgery alone | 54 (79.4) | 14 (100) | |
| Surgery + chemotherapy | 9 (13.2) | 0 (0.0) | |
| Surgery + radiotherapy | 5 (7.5) | 0 (0.0) | |
| Treatment for NPC | 0.957# | ||
| Radiotherapy alone | 4 (5.9) | 1 (7.15) | |
| CCRT | 22 (32.4) | 5 (35.7) | |
| NAC + CCRT | 38 (55.9) | 7 (50.0) | |
| CCRT + AC | 4 (5.9) | 1 (7.15) | |
| Irradiation technique | 1.000& | ||
| 2D-RT | 7 (10.3) | 1 (7.1) | |
| IMRT | 61 (89.7) | 13 (92.9) | |
