Fig. 5
From: TES functions as a Mena-dependent tumor suppressor in gastric cancer carcinogenesis and metastasis
TES inhibits migration and invasion of GC cells in a Mena-dependent fashion. a Expression of TES and Mena in siMena-transfected MKN45 cells was detected by Western blotting. Overexpression of TES significantly suppressed the migration (b) and invasion (c) of siNC-transfected MKN45 cells compared with those of siMena-transfected MKN45 cells. Control: MKN45 cells transfected with Ad-Control and siNC. siMena: MKN45 cells transfected with Ad-Control and siMena. Ad-TES: MKN45 cells transfected with Ad-TES and siNC. Ad-TES + siMena: MKN45 cells transfected with Ad-TES and siMena. The results are expressed as the mean ± SD of three independent experiments. Magnification: ×200. *P < 0.05