Incidence, mortality, and temporal patterns of oropharyngeal cancer in China: a population-based study

Cancer Communications

Table 3 Trends of incidence and mortality of OPC in China, 2003–2012

Item	PC (%)	Trend 1^#					Trend 2^#
Item	PC (%)	APC (%)	95% CI (%)	Period	t	P	APC (%)	95% CI (%)	Period	t	P
Incidence
Total	27.0	6.2	0.5 to 12.3	2003–2006	2.802	0.038	0.7	− 1.2 to 2.6	2007–2012	0.937	0.392
Urban areas	20.4	8.5	0.0 to 17.6	2003–2005	2.582	0.049	0.3	− 0.8 to 1.4	2006–2012	0.633	0.554
Rural areas	61.1	6.0	3.8 to 8.2	2003–2012	6.333	< 0.001	–	–	–	–	–
Males	30.7	2.5	1.5 to 3.5	2003–2012	5.951	< 0.001	–	–	–	–	–
Females	17.7	5.5	− 0.9 to 12.3	2003–2007	2.181	0.081	− 1.6	− 5.9 to 2.9	2008–2012	− 0.932	0.394
Mortality
Total	23.9	2.5	1.7 to 3.3	2003–2012	7.165	< 0.001	–	–	–	–	–
Urban areas	22.3	2.3	1.4 to 3.1	2003–2012	6.037	< 0.001	–	–	–	–	–
Rural areas	25.9	3.2	0.9 to 5.6	2003–2012	3.275	0.011	–	–	–	–	–
Males	33.6	2.9	2.0 to 3.9	2003–2012	7.156	< 0.001	–	–	–	–	–
Females	− 3.6	0.8	− 1.1 to 2.7	2003–2012	0.945	0.372	–	–	–	–	–

PC percentage change, APC annual percentage change, CI confidence interval
^#The program started with the minimum number of joinpoint (e.g., 0 joinpoint, which is a straight line) and tested whether more joinpoints are statistically significant and must be added to the model (up to that maximum number), enabling the user to test whether an apparent change in trend is statistically significant. The significance was tested using a Monte Carlo Permutation method. To reduce the possibility of reporting spurious changes in trends over the period, all models were restricted to a maximum of 2 joinpoints