Skip to main content

Advertisement

Fig. 5 | Cancer Communications

Fig. 5

From: The genomics of desmoplastic small round cell tumor reveals the deregulation of genes related to DNA damage response, epithelial–mesenchymal transition, and immune response

Fig. 5

Copy number alteration (CNA) landscape of DSRCTs. a Genome-wide frequency of CNAs according to EXCAVATOR2 in the six cases of DSRCT; copy number gains and losses are reported in red and blue, respectively. b Gains and losses across the six cases for DDR network (left part) and MErT/EMT (right part). CNA events are colored according to EXCAVATOR2 copy number call. On the top are the genes belonging to these CNAs and their corresponding cytoband. Numbers on the box represent the number of genes involved. The cases are classified into three groups (see coloured vertical bars on the left). MErT, mesenchymal–epithelial reverse transition; hybrid, hybrid/partial epithelial–mesenchymal transition; EMT, epithelial–mesenchymal transition. Gene names: ATXN2, ataxin 2; TAF7, TATA box-binding protein-associated factor; BRWD1, bromodomain and WD repeat domain containing 1; HMGN1, high mobility group nucleosome-binding domain 1; PCDH, protocadherin; KRTAP, keratin-associated protein; LCE, late cornified envelope; SPRR, small proline-rich protein; CRCT1, cysteine-rich C-terminal 1; ETS2, ETS proto-oncogene 2; FOXQ1, forkhead box Q1; FOXF2, forkhead box F2

Back to article page