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Table 4 Adverse events of the enrolled patients after hepatectomy from the day of randomization to the last day of follow-up

From: Adjuvant transcatheter arterial chemoembolization after curative resection for hepatocellular carcinoma patients with solitary tumor and microvascular invasion: a randomized clinical trial of efficacy and safety

Adverse events Hepatectomy-TACE group (n = 116) Hepatectomy Alone group (n = 118) P-value
Grade 1–2 Grade 3–4 Grade 1–2 Grade 3–4
Neutropenia 16 6 6 2 0.006
Anemia 8 2 4 2 0.312
Thrombocytopenia 15 4 3 1 < 0.001
Fever 29 3 4 0 < 0.001
Pain 16 2 5 1 0.010
Nausea/vomiting 26 1 2 0 < 0.001
Liver dysfunction 39 5 6 3 < 0.001
Fatigue 12 2 4 1 0.032
  1. Hepatectomy-TACE: radical hepatectomy followed by adjuvant transcatheter arterial chemoembolization; Hepatectomy Alone: had undergone only radical hepatectomy