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Table 4 Adverse events of the enrolled patients after hepatectomy from the day of randomization to the last day of follow-up

From: Adjuvant transcatheter arterial chemoembolization after curative resection for hepatocellular carcinoma patients with solitary tumor and microvascular invasion: a randomized clinical trial of efficacy and safety

Adverse events

Hepatectomy-TACE group (n = 116)

Hepatectomy Alone group (n = 118)

P-value

Grade 1–2

Grade 3–4

Grade 1–2

Grade 3–4

Neutropenia

16

6

6

2

0.006

Anemia

8

2

4

2

0.312

Thrombocytopenia

15

4

3

1

< 0.001

Fever

29

3

4

0

< 0.001

Pain

16

2

5

1

0.010

Nausea/vomiting

26

1

2

0

< 0.001

Liver dysfunction

39

5

6

3

< 0.001

Fatigue

12

2

4

1

0.032

  1. Hepatectomy-TACE: radical hepatectomy followed by adjuvant transcatheter arterial chemoembolization; Hepatectomy Alone: had undergone only radical hepatectomy