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Fig. 6 | Cancer Communications

Fig. 6

From: Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response

Fig. 6

Application of MiniPDX assay in clinical setting. Representative clinical case study of MiniPDX assay in patient MDX245, with bilateral multiple pulmonary metastases from low grade endometrial stromal sarcoma. a Response of MDX245 patient’s MiniPDX model to single agent apatinib and combined apatinib with olapanib. (n = 6; *, P < 0.05 in comparison to the vehicle group); bc Chest CT scans of patient MDX245, before and 4 months after treatment. Note a significant eradiation in bilateral multiple masses including a massive one (dotted oval). Ola olapanib, Apa apatinib, Pazo pazopanib

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