Fig. 6From: Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic responseApplication of MiniPDX assay in clinical setting. Representative clinical case study of MiniPDX assay in patient MDX245, with bilateral multiple pulmonary metastases from low grade endometrial stromal sarcoma. a Response of MDX245 patient’s MiniPDX model to single agent apatinib and combined apatinib with olapanib. (n = 6; *, P < 0.05 in comparison to the vehicle group); b, c Chest CT scans of patient MDX245, before and 4 months after treatment. Note a significant eradiation in bilateral multiple masses including a massive one (dotted oval). Ola olapanib, Apa apatinib, Pazo pazopanibBack to article page