Skip to main content

Advertisement

Table 1 Comparison of the different characteristics between patients from the Sun Yat-sen University Cancer Center and those from the Fujian Provincial Cancer Hospital’s cohort [14]

From: External validity of a prognostic nomogram for locoregionally advanced nasopharyngeal carcinoma based on the 8th edition of the AJCC/UICC staging system: a retrospective cohort study

Characteristics Sun Yat-sen University Cancer Center patients cohort
n (%)
Fujian Provincial Cancer Hospital cohort
n (%)
Total 535 1197
Age (years)a
 Median (range) 45 (20–72) 46 (11–84)
 Mean 45.4 46.4
The 8th AJCC/UICC clinical stage [cases (%)]a
 III 421 (78.7) 381 (31.8)
 IVa–b 114 (21.3) 462 (38.6)
GTVp (cm3)a
 Median (range) 33.8 (2.6–165.2) 32.8 (0.1–235.6)
 Mean 41.0 41.2
LDH (U/L)a
 Median (range) 165.4 (101.8–448.6) 183 (106–751)
 Mean 171.3 193.4
Sex
 Male 382 (71.4) 905 (75.6)
 Female 153 (28.6) 292 (24.4)
Histologyb
 II 27 (5.0) 51 (4.3)
 III 508 (95.0) 1134 (94.7)
The 8th AJCC/UICC T-classification
 T1 22 (4.1) 285 (23.8)
 T2 45 (8.4) 220 (18.4)
 T3 389 (72.7) 294 (24.6)
 T4 79 (14.8) 398 (33.2)
The 8th AJCC/UICC N-classification
 N0 73 (13.6) 174 (14.5)
 N1 268 (50.1) 658 (55.0)
 N2 149 (27.9) 270 (22.6)
 N3 45 (8.4) 95 (7.9)
The 7th AJCC/UICC T-classification
 T1 22 (4.1) NA
 T2 43 (8.0) NA
 T3 325 (60.7) NA
 T4 145 (27.1) NA
The 7th AJCC/UICC N-classification
 N0 73 (13.6) NA
 N1 273 (51.0) NA
 N2 162 (30.3) NA
 N3a 11 (2.1) NA
 N3b 16 (3.0) NA
The 7th AJCC/UICC clinical stage
 III 367 (68.6) NA
 IVa 141 (26.4) NA
 IVb 27 (5.0) NA
EBV DNA (103 copies/mL)a
 Median (range) 1.65 (0–12,600) NA
 Mean 97.9 NA
EBV DNA (copies/mL)c
 < 103 246 (46.0) NA
 103–104 120 (22.4) NA
 104–105 110 (20.6) NA
 105–106 52 (9.7) NA
 ≥ 106 7 (1.3) NA
Hb (g/L)
 Median (range) 143.0 (88.0–183.0) 143 (80–171)
 Mean 141.6 143
BMI (kg/m2)
 Median (range) 23.0 (15.2–39.7) NA
 Mean 23.1 NA
Chemotherapy
 None 0 (0.0) 181 (15.1)
 Concurrent 535 (100.0) NA
 Other 0 (0.0) NA
  1. AJCC American Joint Committee on Cancer, UICC Union for International Cancer Control, GTVp gross primary tumor volume, LDH lactate dehydrogenase, NA not available, EBV DNA Epstein–Barr virus deoxyribonucleic acid, Hb hemoglobin, BMI body mass index
  2. aCharacteristic included in Pan’s nomogram
  3. bBased on the criteria of the WHO histological type (1991): II differentiated non-keratinizing carcinoma, III undifferentiated non-keratinizing carcinoma
  4. cAs categorized in a previous study [26]