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Table 1 Comparison of the different characteristics between patients from the Sun Yat-sen University Cancer Center and those from the Fujian Provincial Cancer Hospital’s cohort [14]

From: External validity of a prognostic nomogram for locoregionally advanced nasopharyngeal carcinoma based on the 8th edition of the AJCC/UICC staging system: a retrospective cohort study

Characteristics

Sun Yat-sen University Cancer Center patients cohort

n (%)

Fujian Provincial Cancer Hospital cohort

n (%)

Total

535

1197

Age (years)a

 Median (range)

45 (20–72)

46 (11–84)

 Mean

45.4

46.4

The 8th AJCC/UICC clinical stage [cases (%)]a

 III

421 (78.7)

381 (31.8)

 IVa–b

114 (21.3)

462 (38.6)

GTVp (cm3)a

 Median (range)

33.8 (2.6–165.2)

32.8 (0.1–235.6)

 Mean

41.0

41.2

LDH (U/L)a

 Median (range)

165.4 (101.8–448.6)

183 (106–751)

 Mean

171.3

193.4

Sex

 Male

382 (71.4)

905 (75.6)

 Female

153 (28.6)

292 (24.4)

Histologyb

 II

27 (5.0)

51 (4.3)

 III

508 (95.0)

1134 (94.7)

The 8th AJCC/UICC T-classification

 T1

22 (4.1)

285 (23.8)

 T2

45 (8.4)

220 (18.4)

 T3

389 (72.7)

294 (24.6)

 T4

79 (14.8)

398 (33.2)

The 8th AJCC/UICC N-classification

 N0

73 (13.6)

174 (14.5)

 N1

268 (50.1)

658 (55.0)

 N2

149 (27.9)

270 (22.6)

 N3

45 (8.4)

95 (7.9)

The 7th AJCC/UICC T-classification

 T1

22 (4.1)

NA

 T2

43 (8.0)

NA

 T3

325 (60.7)

NA

 T4

145 (27.1)

NA

The 7th AJCC/UICC N-classification

 N0

73 (13.6)

NA

 N1

273 (51.0)

NA

 N2

162 (30.3)

NA

 N3a

11 (2.1)

NA

 N3b

16 (3.0)

NA

The 7th AJCC/UICC clinical stage

 III

367 (68.6)

NA

 IVa

141 (26.4)

NA

 IVb

27 (5.0)

NA

EBV DNA (103 copies/mL)a

 Median (range)

1.65 (0–12,600)

NA

 Mean

97.9

NA

EBV DNA (copies/mL)c

 < 103

246 (46.0)

NA

 103–104

120 (22.4)

NA

 104–105

110 (20.6)

NA

 105–106

52 (9.7)

NA

 ≥ 106

7 (1.3)

NA

Hb (g/L)

 Median (range)

143.0 (88.0–183.0)

143 (80–171)

 Mean

141.6

143

BMI (kg/m2)

 Median (range)

23.0 (15.2–39.7)

NA

 Mean

23.1

NA

Chemotherapy

 None

0 (0.0)

181 (15.1)

 Concurrent

535 (100.0)

NA

 Other

0 (0.0)

NA

  1. AJCC American Joint Committee on Cancer, UICC Union for International Cancer Control, GTVp gross primary tumor volume, LDH lactate dehydrogenase, NA not available, EBV DNA Epstein–Barr virus deoxyribonucleic acid, Hb hemoglobin, BMI body mass index
  2. aCharacteristic included in Pan’s nomogram
  3. bBased on the criteria of the WHO histological type (1991): II differentiated non-keratinizing carcinoma, III undifferentiated non-keratinizing carcinoma
  4. cAs categorized in a previous study [26]