Fig. 11
From: Phenformin alone or combined with gefitinib inhibits bladder cancer via AMPK and EGFR pathways
Effects of the combination of gefitinib with phenformin on EGFR phosphorylation. Western blot analysis was used to examine total (t) and phosphorylated (p) forms of EGFR in MB49, T24, and UMUC3 cells treated with phenformin, gefitinib or their combination. a–c Western blotting of p-EGFR and t-EGFR. β-actin was included as a loading control. d–f Relative levels of phosphorylated EGFR. Results are mean ± SD. *P < 0.05, #P < 0.01 vs. control