Skip to main content

Advertisement

Table 2 Univariate Cox regression analysis of potential prognostic factors for ESCC patients

From: NS1-binding protein radiosensitizes esophageal squamous cell carcinoma by transcriptionally suppressing c-Myc

Variables Learning cohort Validation cohort
HR (95% CI) P* HR (95% CI) P*
Age (years)
 ≤ 55a 1.000   1.000  
 > 55 1.075 (0.743–1.398) 0.826 1.115 (0.673–1.375) 0.747
Gender
 Male 1.000   1.000  
 Female 0.673 (0.512–0.887) 0.036 0.596 (0.425–0.862) 0.041
WHO grade
 G1 1.000   1.000  
 G2 1.376 (0.373–3.746) 0.019 1.542 (0.538–4.137) 0.033
 G3/4 2.479 (0.469–4.837) < 0.001 2.058 (0.558–6.726) < 0.001
T category
 T2–3 1.000   1.000  
 T4 5.475 (2.886–14.137) 0.014 6.889 (2.135–19.559) 0.008
N category
 N0 1.000   1.000  
 N1 9.963 (4.472–18.336) < 0.001 12.559 (6.838–16.945) < 0.001
M category
 M0 1.000   1.000  
 M1-lymb 21.958 (11.028–67.559) < 0.001 16.996 (7.459–70.137) < 0.001
CRT response
 CR 1.000   1.000  
 Not CR 18.965 (13.447–78.775) 0.007 22.598 (9.589–56.779 < 0.001
NS1-BP expression
 High 1.000   1.000  
 Low 16.795 (9.984–52.694) 0.002 21.821 (14.470–68.632) < 0.001
  1. ESCC esophageal squamous cell carcinoma, T tumor, N node, M metastases, CR complete response
  2. 2 test
  3. aMean age
  4. bDistant lymph node metastases