Table 2 Univariate Cox regression analysis of potential prognostic factors for ESCC patients
Variables | Learning cohort | Validation cohort | ||
|---|---|---|---|---|
HR (95% CI) | P* | HR (95% CI) | P* | |
Age (years) | ||||
 ≤ 55a | 1.000 |  | 1.000 |  |
 > 55 | 1.075 (0.743–1.398) | 0.826 | 1.115 (0.673–1.375) | 0.747 |
Gender | ||||
 Male | 1.000 |  | 1.000 |  |
 Female | 0.673 (0.512–0.887) | 0.036 | 0.596 (0.425–0.862) | 0.041 |
WHO grade | ||||
 G1 | 1.000 |  | 1.000 |  |
 G2 | 1.376 (0.373–3.746) | 0.019 | 1.542 (0.538–4.137) | 0.033 |
 G3/4 | 2.479 (0.469–4.837) | < 0.001 | 2.058 (0.558–6.726) | < 0.001 |
T category | ||||
 T2–3 | 1.000 |  | 1.000 |  |
 T4 | 5.475 (2.886–14.137) | 0.014 | 6.889 (2.135–19.559) | 0.008 |
N category | ||||
 N0 | 1.000 |  | 1.000 |  |
 N1 | 9.963 (4.472–18.336) | < 0.001 | 12.559 (6.838–16.945) | < 0.001 |
M category | ||||
 M0 | 1.000 |  | 1.000 |  |
 M1-lymb | 21.958 (11.028–67.559) | < 0.001 | 16.996 (7.459–70.137) | < 0.001 |
CRT response | ||||
 CR | 1.000 |  | 1.000 |  |
 Not CR | 18.965 (13.447–78.775) | 0.007 | 22.598 (9.589–56.779 | < 0.001 |
NS1-BP expression | ||||
 High | 1.000 |  | 1.000 |  |
 Low | 16.795 (9.984–52.694) | 0.002 | 21.821 (14.470–68.632) | < 0.001 |