Table 1 Clinical characteristics of non-small cell lung cancer patients with different failure sites
Factor | Total [cases (%)] | CF [cases (%)] | BF [cases (%)] | OF [cases (%)] | P |
|---|---|---|---|---|---|
Total | 307 | 192 | 32 | 83 | |
Gender | Â | Â | Â | Â | 0.010 |
 Male | 135 (44.0) | 90 (46.9) | 19 (59.4) | 26 (31.3) |  |
 Female | 172 (56.0) | 102 (53.1) | 13 (40.6) | 57 (68.7) |  |
Smoking history | Â | Â | Â | Â | 0.242 |
 Never | 229 (74.6) | 145 (75.5) | 20 (62.5) | 64 (77.1) |  |
 Former/current | 78 (25.4) | 47 (24.5) | 12 (37.5) | 19 (22.9) |  |
Pathology | Â | Â | Â | Â | 0.776 |
 Adenocarcinoma | 298 (97.1) | 186 (96.9) | 31 (96.9) | 81 (97.6) |  |
 Squamous | 4 (1.3) | 2 (1.0) | 1 (3.1) | 1 (1.2) |  |
 Adenosquamous | 5 (1.6) | 4 (2.1) | 0 (0) | 1 (1.2) |  |
Tumor stage | Â | Â | Â | Â | NA |
 IIIA | 52 (16.9) | 51 (26.6) | 0 (0) | 0 (0) |  |
 IIIB | 20 (6.5) | 19 (9.9) | 0 (0) | 0 (0) |  |
 IV | 235 (76.5) | 122 (63.5) | 32 (100) | 83 (100) |  |
Initial EGFR mutation | Â | Â | Â | Â | 0.656 |
 19del | 163 (53.1) | 106 (55.2) | 18 (56.3) | 39 (47.0) |  |
 L858R | 121 (39.4) | 74 (38.5) | 11 (34.4) | 36 (43.4) |  |
 Rare mutation | 23 (7.5) | 12 (6.3) | 3 (9.4) | 8 (9.6) |  |
Response | Â | Â | Â | Â | 0.023 |
 SD | 101 (32.9) | 63 (32.8) | 15 (46.9) | 23 (27.7) |  |
 PR | 180 (58.6) | 116 (60.4) | 17 (53.1) | 47 (56.6) |  |
 CR | 26 (8.5) | 13 (6.8) | 0 (0) | 13 (15.7) |  |