Table 2 Summary of acute adverse effects in 45 patients treated with bevacizumab in combination with neoadjuvant chemoradiotherapy
Toxicity (NCI-CTC Version 3.0) | No. of patients | |||
|---|---|---|---|---|
Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
Hematological | ||||
 Leukopenia | 11 | 8 | 3 | 1 |
 Neutropenia | 16 | 6 | 1 | 1 |
 Thrombocytopenia | 1 | 0 | 0 | 0 |
Non-hematological | ||||
 Diarrhea | 10 | 2 | 2 | 0 |
 Nausea or vomiting | 17 | 2 | 0 | 0 |
 Hand-foot syndrome | 3 | 0 | 0 | 0 |
 Radiation dermatitis | 4 | 0 | 1 | 0 |
 Neuropathy | 15 | 0 | 0 | 0 |
 Proteinuria | 2 | 0 | 0 | 0 |