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Table 2 Summary of acute adverse effects in 45 patients treated with bevacizumab in combination with neoadjuvant chemoradiotherapy

From: Neoadjuvant oxaliplatin and capecitabine combined with bevacizumab plus radiotherapy for locally advanced rectal cancer: results of a single-institute phase II study

Toxicity (NCI-CTC Version 3.0) No. of patients
Grade 1 Grade 2 Grade 3 Grade 4
Hematological
 Leukopenia 11 8 3 1
 Neutropenia 16 6 1 1
 Thrombocytopenia 1 0 0 0
Non-hematological
 Diarrhea 10 2 2 0
 Nausea or vomiting 17 2 0 0
 Hand-foot syndrome 3 0 0 0
 Radiation dermatitis 4 0 1 0
 Neuropathy 15 0 0 0
 Proteinuria 2 0 0 0