From: Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study
Variable | Patients [cases (%)] |
---|---|
Total | 527 |
Male | 348 (66.0) |
Primary cancer | |
Colorectal | 378 (71.7) |
Gastric | 123 (23.3) |
Head and neck | 15 (2.9) |
Esophageal | 6 (1.1) |
Breast | 4 (0.8) |
Nasopharyngeal | 1 (0.2) |
Cancer stage | |
I | 2 (0.4) |
II | 105 (20.0) |
III | 249 (47.2) |
IV | 153 (29.0) |
Not available | 18 (3.4) |
Pre-existing disease | |
Hypertension | 106 (20.1) |
Diabetes | 29 (5.5) |
Cardiac disease | 13 (2.5) |
Hyperlipidemia | 4 (0.8) |
Surgical history | 415 (78.7) |
Radical | 338 (64.1) |
Palliative | 57 (10.8) |
Unknown | 20 (3.8) |
Treatment history | 176 (33.4) |
Chemotherapy | 118 (22.4) |
Radiotherapy | 32 (6.1) |
Chemotherapy and radiotherapy | 26 (4.9) |