Fig. 7From: Efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in nasopharyngeal carcinoma in vitro and in vivoDetection of tumor hypoxic regions by immunohistochemical staining with pimonidazole. Pimonidazole-positive hypoxic areas in the whole tumor (hypoxic fraction) were extracted using Image-Pro Plus 6.0 for three animals in each group. Representative images at 100× magnification are shown. Statistical results are shown in the graph. *P < 0.05Back to article page