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Table 5 Time trends of age-standardized mortality rates from common cancers among males in Serbia, 1991–2015, by joinpoint analysis

From: Cancer mortality in Serbia, 1991–2015: an age-period-cohort and joinpoint regression analysis

Cancer site AAPC (95% CI) Trend 1 APC (95% CI) Trend 2 APC (95% CI) Trend 3 APC (95% CI)
Lung 1.0* (0.7 to 1.2) 1991–2009 1.4* (1.1 to 1.6) 2009–2015 − 1.1 (− 2.4 to 0.2) None
Colon 1.6* (1.3 to 1.8) 1991–2009 2.0* (1.7 to 2.3) 2009–2015 − 0.3 (− 1.9 to 1.2) None
Stomach −  2.1* (− 2.4 to − 1.8) 1991–2009 − 1.6* (− 1.9 to − 1.3) 2009–2015 − 4.6* (− 6.2 to − 2.9) None
Hematological malignancies 0.7* (0.3 to 1.1) 1991–1998 − 3.0* (− 4.2 to − 1.9) 1998–2007 3.0* (2.0 to 4.0) 2007–2015 − 0.4 (− 1.4 to 0.6)
Brain 1.2* (0.6 to 1.7) 1991–1993 17.8 (− 5.9 to 47.6) 1993–2015 0.8* (0.2 to 1.3) None
Bladder 0.9* (0.4 to 1.3) None None None
Pancreas 1.4* (1.1 to 1.7) 1991–1993 − 5.6 (− 17.5 to 1.3) 1993–2015 1.6* (1.3 to 1.9) None
Prostate 1.9* (1.4 to 2.3) None None None
Renal 1.4* (0.9 to 1.8) None None None
All sites 0.6* (0.5 to 0.8) 1991–2009 0.9* (0.8 to 1.0) 2009–2015 − 0.9* (− 1.6 to − 0.2) None
  1. AAPC average annual percent change; APC annual percent change; CI confidence interval
  2. * Statistically significant trend