Table 1 Characteristics of 862 ESCC patients with or without T2DM
Characteristic | Before matching | After matching | ||||||
|---|---|---|---|---|---|---|---|---|
No. of cases (%) | With T2DM (%) | Without T2DM (%) | P valuea | No. of cases (%) | With T2DM (%) | Without T2DM (%) | P valuea | |
Age (years) | 0.012 | 0.499 | ||||||
≤ 45 | 48 (5.6) | 4 (1.4) | 44 (7.6) | 13 (2.3) | 4 (1.4) | 9 (3.2) | ||
46–59 | 370 (42.9) | 112 (40.0) | 258 (44.3) | 225 (40.2) | 112 (40.0) | 113 (40.4) | ||
≥ 60 | 444 (51.5) | 164 (58.6) | 280 (48.1) | 322 (57.5) | 164 (58.6) | 158 (56.4) | ||
Sex | 0.024 | 0.330 | ||||||
Female | 224 (26.0) | 92 (32.9) | 132 (22.7) | 195 (34.8) | 92 (32.9) | 103 (36.8) | ||
Male | 638 (74.0) | 188 (67.1) | 450 (77.3) | 365 (65.2) | 188 (67.1) | 177 (63.2) | ||
Smoking status | < 0.001 | 0.798 | ||||||
Yes | 362 (42.0) | 160 (57.1) | 202 (34.7) | 317 (56.6) | 160 (57.1) | 157 (56.1) | ||
No | 500 (58.0) | 120 (42.9) | 380 (65.3) | 243 (43.4) | 120 (42.9) | 123 (43.9) | ||
Drinking status | 0.060 | 0.754 | ||||||
Yes | 638 (74.0) | 224 (80.0) | 414 (71.1) | 445 (79.5) | 224 (80.0) | 221 (78.9) | ||
No | 224 (26.0) | 56 (20.0) | 168 (28.9) | 115 (20.5) | 56 (20.0) | 59 (21.1) | ||
Weight loss rate | 0.705 | 0.976 | ||||||
0 | 474 (55.0) | 144 (51.4) | 330 (56.7) | 292 (52.1) | 144 (51.4) | 148 (52.9) | ||
> 0% to ≤ 5% | 152 (17.6) | 56 (20.0) | 96 (16.5) | 102 (36.4) | 56 (20.0) | 46 (16.4) | ||
> 5% to ≤ 10% | 182 (21.1) | 60 (21.4) | 122 (21.0) | 126 (22.5) | 60 (21.4) | 66 (23.6) | ||
> 10% | 54 (6.3) | 20 (7.2) | 34 (5.8) | 40 (7.1) | 20 (7.1) | 20 (7.1) | ||
BMI (kg/m2) | 0.006 | 0.409 | ||||||
< 18.5 | 76 (8.8) | 8 (2.9) | 68 (11.7) | 34 (6.0) | 8 (2.9) | 26 (9.3) | ||
≥ 18.5 to < 25.0 | 622 (72.2) | 208 (74.3) | 414 (71.1) | 393 (70.2) | 208 (74.3) | 185 (66.1) | ||
≥ 25.0 | 164 (19.0) | 64 (22.8) | 100 (17.2) | 133 (23.8) | 64 (22.9) | 69 (24.6) | ||
Tumor location | 0.052 | 0.590 | ||||||
Upper | 58 (6.7) | 20 (7.1) | 38 (6.5) | 34 (6.0) | 20 (7.1) | 14 (5.0) | ||
Middle | 560 (65.0) | 160 (57.2) | 400 (68.7) | 337 (60.2) | 160 (57.1) | 177 (63.2) | ||
Lower | 244 (28.3) | 100 (35.7) | 144 (24.8) | 189 (33.8) | 100 (35.7) | 89 (31.8) | ||
Tumor grade | 0.206 | 0.992 | ||||||
G1 | 232 (26.9) | 80 (28.6) | 152 (26.1) | 148 (26.4) | 80 (28.6) | 68 (24.3) | ||
G2 | 386 (44.8) | 120 (42.8) | 266 (45.7) | 264 (47.2) | 120 (42.9) | 144 (51.4) | ||
G3 | 244 (28.3) | 80 (28.6) | 164 (28.2) | 148 (26.4) | 80 (28.5) | 68 (24.3) | ||
pT category | 0.231 | 0.236 | ||||||
T1 | 48 (5.6) | 8 (2.9) | 40 (6.9) | 18 (3.2) | 8 (2.9) | 10 (3.6) | ||
T2 | 232 (26.9) | 76 (27.1) | 156 (26.8) | 163 (29.1) | 76 (27.1) | 87 (31.1) | ||
T3 | 582 (67.5) | 196 (70.0) | 386 (66.3) | 379 (67.7) | 196 (70.0) | 183 (65.3) | ||
pN category | 0.284 | 0.870 | ||||||
N0 | 476 (55.2) | 144 (51.4) | 332 (57.1) | 285 (50.9) | 144 (51.4) | 141 (50.4) | ||
N1 | 242 (28.1) | 80 (28.6) | 162 (27.8) | 172 (30.7) | 80 (28.6) | 92 (32.8) | ||
N2 | 124 (14.4) | 52 (18.6) | 72 (12.4) | 96 (17.1) | 52 (18.6) | 44 (15.7) | ||
N3 | 20 (2.3) | 4 (1.4) | 16 (2.7) | 7 (1.3) | 4 (1.4) | 3 (1.1) | ||
pTNM stage | 0.161 | 0.947 | ||||||
Stage I | 46 (5.3) | 8 (2.9) | 38 (6.5) | 20 (3.6) | 8 (2.9) | 12 (4.3) | ||
Stage II | 450 (52.2) | 140 (50.0) | 310 (53.3) | 273 (48.7) | 140 (50.0) | 133 (47.5) | ||
Stage III | 366 (42.5) | 132 (47.1) | 234 (40.2) | 267 (47.7) | 132 (47.1) | 135 (48.2) | ||
Complication | ||||||||
None | 718 (83.3) | 216 (77.1) | 502 (86.3) | 0.018 | 458 (81.8) | 216 (77.1) | 242 (86.4) | 0.004 |
Anastomotic leakage | 82 (9.5) | 48 (17.1) | 34 (5.8) | 0.001 | 60 (10.7) | 48 (17.1) | 12 (4.3) | < 0.0001 |
Pneumonia | 32 (3.7) | 8 (2.9) | 24 (4.1) | 0.515 | 22 (3.9) | 8 (2.9) | 14 (5.0) | 0.192 |
Othersb | 30 (3.5) | 8 (2.9) | 22 (3.8) | 0.624 | 20 (3.6) | 8 (2.9) | 12 (4.3) | 0.363 |
Total | 862 | 280 | 582 | 560 | 280 | 280 | ||