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Table 4 Univariate and multivariate analyses of prognostic factors for DFS of TNBC patients

From: Genetic polymorphisms of autophagy-related gene 5 (ATG5) rs473543 predict different disease-free survivals of triple-negative breast cancer patients receiving anthracycline- and/or taxane-based adjuvant chemotherapy

Characteristic Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
Age (≤ 40 vs. > 40 years) 1.038 (0.614–1.752) 0.890  
T stage (pT0–T1 vs. pT2-T4) 1.393 (0.897–2.164) 0.140  
Family history of breast cancer (yes vs. no) 0.771 (0.386–1.543) 0.463  
Axillary lymph node status (negative vs. positive) 2.507 (1.615–3.890) < 0.001 2.055 (1.190–3.547) 0.010
TNM stage (0-I vs. II-III) 2.063 (1.221–3.485) 0.007 1.237 (0.653–2.346) 0.514
Pathological type (invasive ductal carcinoma vs. others) 0.874 (0.450–1.695) 0.689  
Vascular invasion (yes vs. no) 2.486 (1.497–4.126) < 0.001 1.901 (1.124–3.216) 0.017
ATG5 rs473543 genotype (AA/GA vs. GG) 1.717 (1.036–2.847) 0.036 1.729 (1.041–2.870) 0.034
  1. HR hazard ratio, CI confidence interval, not included