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Table 3 The relationship between ATG5 rs473543 genotypes and DFS in the recurrent group and the non-recurrent group of TNBC patients

From: Genetic polymorphisms of autophagy-related gene 5 (ATG5) rs473543 predict different disease-free survivals of triple-negative breast cancer patients receiving anthracycline- and/or taxane-based adjuvant chemotherapy

Characteristic Non-recurrent group (cases) Recurrent group (cases) P value
AA/GA GG AA/GA GG
Total 143 92 61 20  
Age (years)
 ≤ 40 36 20 15 3 0.139
 > 40 107 72 46 17 0.093
Family history of breast cancer
 Yes 18 17 8 1 0.081
 No 125 75 53 19 0.122
Axillary lymph node status
 Negative 102 61 30 6 0.027
 Positive 41 31 31 14 0.229
TNM stage      
 0–I 56 35 15 3 0.097
 II–III 87 57 46 17 0.127
Invasive ductal carcinoma
 Grade 1/2 47 28 25 9 0.410
 Grade 3 82 49 25 8 0.179
Vascular invasion
 Yes 16 10 15 5 0.444
 No 127 82 46 15 0.068
  1. DFS disease-free survival
  2. In different subclinical groups, the relationship between ATG5 rs473543 genotypes and DFS was analyzed using Kaplan–Meier curves. Differences across survival curves were compared by the log-rank test, the P values for which were shown in this table