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Table 3 The correlation of FSTL1 level with the expression of HIF-1α/2α in ccRCC tissues and tumor stage

From: Follistatin-like protein 1 plays a tumor suppressor role in clear-cell renal cell carcinoma

Variable Immunoreactive scores of FSTL1 (cases) P r s
Negative Positive
HIF-1α expression
 Negative (−) 19 21 0.047 0.216
 Positive (+/++/+++) 12 33   
HIF-2α expression
 Negative (–) 5 21 0.044 − 0.229
 Positive (+/++/+++) 22 30   
AJCC stage
 I 16 39 0.110 − 0.170
 II 3 5   
 III 6 9   
 IV 6 5   
  1. ccRCC clear-cell renal cell carcinoma; FSTL1 follistatin-like protein 1; HIF hypoxia-inducible factor; AJCC American Joint Committee on Cancer; r s Spearman rank correlation coefficient