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Table 3 The correlation of FSTL1 level with the expression of HIF-1α/2α in ccRCC tissues and tumor stage

From: Follistatin-like protein 1 plays a tumor suppressor role in clear-cell renal cell carcinoma

Variable

Immunoreactive scores of FSTL1 (cases)

P

r s

Negative

Positive

HIF-1α expression

 Negative (−)

19

21

0.047

0.216

 Positive (+/++/+++)

12

33

  

HIF-2α expression

 Negative (–)

5

21

0.044

− 0.229

 Positive (+/++/+++)

22

30

  

AJCC stage

 I

16

39

0.110

− 0.170

 II

3

5

  

 III

6

9

  

 IV

6

5

  
  1. ccRCC clear-cell renal cell carcinoma; FSTL1 follistatin-like protein 1; HIF hypoxia-inducible factor; AJCC American Joint Committee on Cancer; r s Spearman rank correlation coefficient