Table 2 Characteristics of breast cancer patients by molecular subtype
Characteristic | Overall | Subtype | P valueb | ||||
|---|---|---|---|---|---|---|---|
Luminal A | Luminal B | HER2 | Triple-negative | Unknowna | |||
Total | 4640 | 2387 | 535 | 365 | 517 | 836 | Â |
Age (years) | 52.9 ± 11.3 | 53.5 ± 11.8 | 51.7 ± 10.6 | 52.9 ± 10.1 | 53.3 ± 11.8 | 53.2 ± 11.8 | 0.01 |
BMI | 25.0 ± 3.8 | 25.1 ± 3.8 | 24.6 ± 3.8 | 25.3 ± 4.1 | 24.9 ± 3.7 | 25.1 ± 3.8 | 0.07 |
Menopausal status | <Â 0.01 | ||||||
 Premenopausal | 2017 (43.5) | 1085 (45.5) | 241 (45.1) | 129 (35.3) | 205 (39.7) | 357 (42.7) |  |
 Postmenopausal | 2510 (54.1) | 1251 (52.4) | 280 (52.3) | 232 (63.6) | 303 (58.6) | 444 (53.1) |  |
 Unknowna | 113 (2.4) | 51 (2.1) | 14 (2.6) | 4 (1.1) | 9 (1.7) | 35 (4.2) |  |
Histological grade | <Â 0.01 | ||||||
 Well differentiated | 349 (7.5) | 227 (9.5) | 24 (4.5) | 12 (3.3) | 18 (3.5) | 68 (8.1) |  |
 Moderately differentiated | 2549 (54.9) | 1414 (59.2) | 319 (59.6) | 180 (49.3) | 207 (40.0) | 429 (51.3) |  |
 Poorly differentiated | 899 (19.4) | 306 (12.8) | 131 (24.5) | 124 (34.0) | 193 (37.3) | 145 (17.4) |  |
 Unknowna | 843 (18.2) | 440 (18.4) | 61 (11.4) | 49 (13.4) | 99 (19.2) | 194 (23.2) |  |
Histological type | <Â 0.01 | ||||||
 Ductal | 4031 (86.9) | 2052 (86.0) | 496 (92.7) | 338 (92.6) | 445 (86.1) | 700 (83.7) |  |
 Lobular | 149 (3.2) | 100 (4.2) | 8 (1.5) | 3 (0.8) | 9 (1.7) | 29 (3.5) |  |
 Others | 460 (9.9) | 235 (9.8) | 31 (5.8) | 24 (6.6) | 63 (12.2) | 107 (12.8) |  |
Stage | <Â 0.01 | ||||||
 I | 1334 (28.7) | 775 (32.5) | 144 (26.9) | 78 (21.4) | 130 (25.2) | 207 (24.7) |  |
 II | 2180 (47.0) | 1122 (47.0) | 246 (46.0) | 178 (48.8) | 241 (46.6) | 393 (47.0) |  |
 III | 573 (12.3) | 267 (11.2) | 72 (13.5) | 67 (18.4) | 81 (15.7) | 86 (10.3) |  |
 IV | 100 (2.2) | 32 (1.3) | 18 (3.4) | 11 (3.0) | 10 (1.9) | 29 (3.5) |  |
 Unknowna | 453 (9.8) | 191 (8.0) | 55 (10.3) | 31 (8.5) | 55 (10.6) | 121 (14.5) |  |