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Table 2 Characteristics of breast cancer patients by molecular subtype

From: The influence of stage at diagnosis and molecular subtype on breast cancer patient survival: a hospital-based multi-center study

Characteristic Overall Subtype P valueb
Luminal A Luminal B HER2 Triple-negative Unknowna
Total 4640 2387 535 365 517 836  
Age (years) 52.9 ± 11.3 53.5 ± 11.8 51.7 ± 10.6 52.9 ± 10.1 53.3 ± 11.8 53.2 ± 11.8 0.01
BMI 25.0 ± 3.8 25.1 ± 3.8 24.6 ± 3.8 25.3 ± 4.1 24.9 ± 3.7 25.1 ± 3.8 0.07
Menopausal status < 0.01
 Premenopausal 2017 (43.5) 1085 (45.5) 241 (45.1) 129 (35.3) 205 (39.7) 357 (42.7)  
 Postmenopausal 2510 (54.1) 1251 (52.4) 280 (52.3) 232 (63.6) 303 (58.6) 444 (53.1)  
 Unknowna 113 (2.4) 51 (2.1) 14 (2.6) 4 (1.1) 9 (1.7) 35 (4.2)  
Histological grade < 0.01
 Well differentiated 349 (7.5) 227 (9.5) 24 (4.5) 12 (3.3) 18 (3.5) 68 (8.1)  
 Moderately differentiated 2549 (54.9) 1414 (59.2) 319 (59.6) 180 (49.3) 207 (40.0) 429 (51.3)  
 Poorly differentiated 899 (19.4) 306 (12.8) 131 (24.5) 124 (34.0) 193 (37.3) 145 (17.4)  
 Unknowna 843 (18.2) 440 (18.4) 61 (11.4) 49 (13.4) 99 (19.2) 194 (23.2)  
Histological type < 0.01
 Ductal 4031 (86.9) 2052 (86.0) 496 (92.7) 338 (92.6) 445 (86.1) 700 (83.7)  
 Lobular 149 (3.2) 100 (4.2) 8 (1.5) 3 (0.8) 9 (1.7) 29 (3.5)  
 Others 460 (9.9) 235 (9.8) 31 (5.8) 24 (6.6) 63 (12.2) 107 (12.8)  
Stage < 0.01
 I 1334 (28.7) 775 (32.5) 144 (26.9) 78 (21.4) 130 (25.2) 207 (24.7)  
 II 2180 (47.0) 1122 (47.0) 246 (46.0) 178 (48.8) 241 (46.6) 393 (47.0)  
 III 573 (12.3) 267 (11.2) 72 (13.5) 67 (18.4) 81 (15.7) 86 (10.3)  
 IV 100 (2.2) 32 (1.3) 18 (3.4) 11 (3.0) 10 (1.9) 29 (3.5)  
 Unknowna 453 (9.8) 191 (8.0) 55 (10.3) 31 (8.5) 55 (10.6) 121 (14.5)  
  1. Continuous data are expressed as mean ± SD. Categorical data are expressed as number of cases (percent)
  2. aUnknown data were not included in the statistical tests
  3. b P values were calculated using one-way ANOVA test (continuous variables) and Chi square or exact test (categorical variables)