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Fig. 4 | Chinese Journal of Cancer

Fig. 4

From: Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer

Fig. 4

Effects of TRIM3 overexpression on the cell cycle and apoptosis of HepG2 and Bel-7402 cells. a, b Effect of TRIM3 overexpression on the cell cycle was determined using flow cytometry. TRIM3 overexpression caused G0/G1 phase arrest in HepG2 (a) and Bel-7402 (b) cells. c, d Effect of TRIM3 overexpression on apoptosis of HepG2 and Bel-7402 cells was determined with Annexin V-propidium iodide (PI) staining method. Apoptosis rates are not significantly different between HepG2 (c) and Bel-7402 (d) cells infected with LV-TRIM3 and those infected with LV-NC. P values were calculated using Student’s t test. *P < 0.05, **P < 0.01, and ***P < 0.001, versus cells infected with LV-NC

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