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Table 5 Multivariate analyses of associations between clinical characteristics and SF-36 scores of mRCC patients

From: Comparison of efficacy, safety, and quality of life between sorafenib and sunitinib as first-line therapy for Chinese patients with metastatic renal cell carcinoma

Variable

PF score

RP score

BP score

GH score

VT score

SF score

RE score

MH score

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

Sex (man vs. woman)

1.611 (0.786–3.302)

0.193

1.419 (0.692–2.909)

0.339

0.737 (0.337–1.613)

0.446

0.884 (0.421–1.885)

0.744

0.861 (0.428–1.730)

0.674

0.955 (0.476–1.917)

0.898

1.673 (0.796–3.513)

0.174

0.850 (0.423–1.710)

0.649

Age (<65 vs. ≥65 years)

0.689 (0.347–1.402)

0.312

0.821 (0.401–1.680)

0.589

0.721 (0.329–1.580)

0.414

0.794 (0.378–1.665)

0.541

1.636 (0.802–3.337)

0.176

0.814 (0.406–1.632)

0.562

1.033 (0.506–2.109)

0.929

1.310 (0.61–2.636)

0.449

MSKCC grade (favorable vs. others)

1.184 (0.441–3.179

0.738

2.557 (0.905–7.339)

0.076

1.089 (0.371–3.195)

0.877

1.927 (0.721–5.153)

0.191

0.887 (0.334–2.357)

0.811

1.939 (0.714–5.265)

0.194

1.128 (0.413–3.085)

0.814

0.804 (0.305–2.122)

0.660

IMDC risk (good vs. others)

0.689 (0.347–1.402)

0.713

0.202 (0.041–1.003)

0.050

0.465 (0.371–3.195)

0.399

0.665 (0.157–2.809)

0.579

0.454 (0.109–1.887)

0.277

0.527 (0.129–2.157)

0.373

1.077 (0.258–4.499)

0.919

1.529 (0.383–6.104)

0.548

AE grade (1–2 vs. 3–4)

0.699 (0.268–1.828)

0.465

3.711 (1.263–10.910)

0.017

4.259 (1.561–11.622)

0.005

1.411 (0.532–3.747)

0.489

0.758 (0.289–1.989)

0.573

1.718 (0.641–4.603)

0.282

2.035 (0.695–5.960)

0.329

2.465 (0.889–6.835)

0.083

Treatment (sorafenib vs. sunitinib)

1.141 (0.620–2.099)

0.671

1.001 (0.539–1.859)

0.998

1.335 (0.694–2.568)

0.387

0.595 (0.311–1.139

0.117

0.735 (0.401–1.348)

0.320

1.033 (0.564–1.890)

0.917

1.364 (0.731–2.545)

0.721

1.340 (0.730–3.462)

0.345

  1. PF physical functioning, RP role-physical, BP bodily pain, GH general health, VT vitality, SF social functioning, RE role-emotional, MH mental health, IMDC International Metastatic Renal Cell Carcinoma Database Consortium
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Cancer Communications

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