|
Variable
|
Overall [cases (%)]
|
TACE group [cases (%)]
|
TACE with H101 group [cases (%)]
|
P value
|
|---|
|
Age (years)
| | | |
0.420
|
|
≤60
|
337 (70.8)
|
164 (68.9)
|
173 (72.7)
| |
|
>60
|
139 (29.2)
|
74 (31.1)
|
65 (27.3)
| |
|
Sex
| | | |
0.877
|
|
Man
|
430 (90.3)
|
214 (89.9)
|
216 (90.8)
| |
|
Woman
|
46 (9.7)
|
24 (10.1)
|
22 (9.2)
| |
|
WBC (×109/L)
| | | |
0.693
|
|
<10
|
449 (94.3)
|
223 (93.7)
|
226 (95.0)
| |
|
≥10
|
27 (5.7)
|
15 (6.7)
|
12 (5.0)
| |
|
PLT (×109/L)
| | | |
0.123
|
|
<100
|
58 (12.2)
|
35 (14.7)
|
23 (9.7)
| |
|
≥100
|
418 (87.8)
|
203 (85.3)
|
215 (90.3)
| |
|
ALT (U/L)
| | | |
0.682
|
|
<40
|
173 (36.3)
|
79 (33.2)
|
94 (39.5)
| |
|
≥40
|
303 (63.7)
|
159 (66.8)
|
144 (60.5)
| |
|
AST (U/L)
| | | |
0.924
|
|
<45
|
168 (35.3)
|
83 (34.9)
|
85 (35.7)
| |
|
≥45
|
308 (64.7)
|
155 (65.1)
|
153 (64.3)
| |
|
ALB (g/L)
| | | |
0.417
|
|
<35
|
63 (13.2)
|
35 (14.7)
|
28 (11.8)
| |
|
≥35
|
413 (86.8)
|
203 (85.3)
|
210 (88.2)
| |
|
TBIL (mmol/L)
| | | |
0.066
|
|
<20
|
381 (80.0)
|
182 (76.5)
|
199 (83.6)
| |
|
≥20
|
95 (20.0)
|
56 (23.5)
|
39 (16.4)
| |
|
IBIL (mmol/L)
| | | |
0.011
|
|
<15
|
431 (90.5)
|
207 (87.0)
|
224 (94.1)
| |
|
≥15
|
45 (9.5)
|
31 (13)
|
14 (5.9)
| |
|
ALP (U/L)
| | | |
0.773
|
|
<100
|
166 (34.9)
|
81 (34.0)
|
85 (35.7)
| |
|
≥100
|
310 (65.1)
|
157 (66.0)
|
153 (64.2)
| |
|
CRP (mg/L)
| | | |
0.714
|
|
<8.2
|
249 (52.3)
|
127 (53.4)
|
122 (51.2)
| |
|
≥8.2
|
227 (47.7)
|
111 (46.6)
|
116 (48.8)
| |
|
AFP (ng/mL)
| | | |
0.923
|
|
<25
|
164 (34.5)
|
81 (34.0)
|
83 (34.8)
| |
|
≥25
|
312 (65.5)
|
157 (66.0)
|
155 (65.2)
| |
|
HBsAg
| | | |
0.046
|
|
Negative
|
27 (5.7)
|
19 (8.0)
|
8 (3.4)
| |
|
Positive
|
449 (94.3)
|
219 (92.0)
|
230 (96.6)
| |
|
HBV-DNA (IU/mL)
| | | |
0.589
|
|
<100
|
112 (23.5)
|
59 (24.8)
|
53 (22.2)
| |
|
≥100
|
364 (76.5)
|
179 (75.2)
|
185 (77.8)
| |
|
NLR
| | | |
0.916
|
|
<3
|
354 (74.4)
|
178 (74.8)
|
176 (73.9)
| |
|
≥3
|
122 (25.6)
|
60 (25.2)
|
62 (26.1)
| |
|
Tumor size (cm)
| | | |
1.000
|
|
<5
|
130 (27.3)
|
65 (27.3)
|
65 (27.3)
| |
|
≥5
|
346 (72.7)
|
173 (72.7)
|
173 (72.7)
| |
|
Tumor number
| | | |
0.391
|
|
Single
|
172 (36.1)
|
91 (38.2)
|
81 (34.0)
| |
|
Multiple
|
304 (63.9)
|
147 (61.8)
|
157 (66.0)
| |
|
Splenomegaly
| | | |
0.177
|
|
No
|
311 (65.3)
|
148 (62.2)
|
163 (68.5)
| |
|
Yes
|
165 (34.7)
|
90 (37.8)
|
75 (31.5)
| |
|
Metastasis
| | | |
0.835
|
|
No
|
452 (95.0)
|
227 (95.4)
|
225 (94.5)
| |
|
Yes
|
24 (5.0)
|
11 (4.6)
|
13 (5.5)
| |
|
Vascular invasion
| | | |
0.763
|
|
No
|
336 (70.6)
|
170 (71.4)
|
166 (69.7)
| |
|
Yes
|
140 (29.4)
|
68 (28.6)
|
72 (30.3)
| |
|
Antiviral therapy
| | | |
0.066
|
|
No
|
251 (52.7)
|
115 (48.3)
|
136 (57.1)
| |
|
Yes
|
225 (47.3)
|
123 (51.7)
|
102 (42.9)
| |
-
WBC white blood cell count, PLT platelet, ALT alanine transaminase, AST aspartate aminotransferase, ALB albumin, TBIL total bilirubin, IBIL indirect bilirubin, ALP alkaline phosphatase, CRP C-reactive protein, AFP alpha-fetoprotein, HBsAg surface antigen of hepatitis B virus, HBV hepatitis B virus, NLR neutrophil-to-lymphocyte ratio
