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Table 4 Associations among PD-L1, PD-L2, and PD-1 expression in metastatic lymph nodes from patients with gastric adenocarcinoma

From: Prognostic value of programmed death-1, programmed death-ligand 1, programmed death-ligand 2 expression, and CD8(+) T cell density in primary tumors and metastatic lymph nodes from patients with stage T1-4N+M0 gastric adenocarcinoma

Variable

PD-L1 expression [cases (%)]

PD-L2 expression [cases (%)]

Negative

Positive

P

Negative

Positive

P

PD-L2 expression

  

0.012

   

 Negative

54 (45.4)

11 (9.2)

    

 Positive

33 (27.7)

21 (17.6)

    

PD-1 expression on CD8(+) T cells

  

0.034

  

0.002

 Negative

45 (37.8)

27 (22.7)

 

60 (50.4)

12 (10.1)

 

 Positive

20 (16.8)

27 (22.7)

 

27 (22.7)

20 (16.8)