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Table 3 Associations among PD-L1, PD-L2, PD-1 expression, and CD8(+) T-cell density in primary tumors from patients with gastric adenocarcinoma

From: Prognostic value of programmed death-1, programmed death-ligand 1, programmed death-ligand 2 expression, and CD8(+) T cell density in primary tumors and metastatic lymph nodes from patients with stage T1-4N+M0 gastric adenocarcinoma

Variable PD-L1 expression [cases (%)] PD-L2 expression [cases (%)]
Negative Positive P Negative Positive P
PD-L2 expression    0.043    
 Negative 57 (47.9) 28 (23.5)     
 Positive 16 (13.4) 18 (15.1)     
Density of CD8(+) T cells    0.022    0.004
 Low 22 (18.5) 24 (20.2)   26 (21.8) 20 (16.8)  
 High 51 (42.9) 22 (18.5)   59 (49.6) 14 (11.8)  
PD-1 expression on CD8(+) T cells    0.162    0.951
 Negative 49 (41.2) 25 (21.0)   53 (44.5) 21 (17.6)  
 Positive 24 (20.2) 21 (17.6)   32 (26.9) 13 (10.9)