Table 7 Summary of drug-related adverse events in the 184 patients with metastatic renal cell carcinoma
Drug-related adverse event | None | Any grade | Grade 1–2 | Grade 3–4 |
|---|---|---|---|---|
Hand-foot syndrome | 63 (34.2) | 121(65.8) | 112 (60.6) | 9 (4.9) |
Diarrhea | 86 (46.7) | 98 (53.3) | 93 (50.5) | 5 (2.7) |
Nausea | 110 (59.8) | 74 (40.2) | 74 (40.2) | 0 (0.0) |
Fatigue | 106 (57.6) | 78 (42.4) | 78 (42.4) | 0 (0.0) |
Hypertension | 125 (69.6) | 59 (32.1) | 55 (29.9) | 4 (2.2) |
Thrombocytopenia | 144 (78.3) | 40 (21.7) | 38 (20.7) | 2 (1.1) |
Leukocytopenia | 147 (79.9) | 37 (20.1) | 35 (19.0) | 2 (1.1) |
Anemia | 156 (84.8) | 28 (15.2) | 26 (14.1) | 2 (1.1) |
Elevation of ALT | 160 (87.0) | 24 (13.0) | 23 (11.5) | 1 (0.5) |
Alopecia | 167 (90.8) | 17 (9.2) | 17 (9.2) | 0 (0.0) |
Hypothyroidism | 168 (91.3) | 16 (8.7) | 16 (8.7) | 0 (0.0) |