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Table 2 Univariate and multivariate Cox regression analyses of disease-free survival of 307 patients with primary thymoma

From: Long-term outcomes of 307 patients after complete thymoma resection

Variable Univariate Multivariate
HR 95% CI P value HR 95% CI P value
Age (years)
  ≤60       
  >60 0.733 0.345–1.558 0.420    
Sex
 Female       
 Male 1.175 0.680–2.028 0.563    
Tumor size (cm) 1.017 0.913–1.132 0.762    
Myasthenia gravis
 Yes       
 No 1.254 0.610–2.580 0.538    
WHO histological classification
 A + AB       
 B1 2.513 0.844–7.481 0.098 1.530 0.492–4.759 0.463
 B2 6.831 2.810–16.604 <0.001 2.855 1.070–7.621 0.036
 B3 7.999 3.032–21.108 <0.001 2.404 0.809–7.141 0.114
Masaoka stage
 I       
 II 2.284 0.669–7.801 0.188 1.211 0.326–4.501 0.775
 III 12.624 3.800–41.943 <0.001 4.935 1.289–18.894 0.020
 IVa 26.872 7.102–101.680 <0.001 13.809 3.230–59.043 <0.001
Surgical approach
 Transthoracic       
 Transsternal 0.803 0.421–1.532 0.506    
 VATS 1.304 0.635–2.676 0.470    
Postoperative radiotherapy
 Yes       
 No 2.212 1.214–4.032 0.010 1.887 0.932–3.823 0.078
  1. CI confidence interval, HR hazard ratio, WHO World Health Organization, VATS video-assisted thoracoscopic surgery