Table 2 Univariate and multivariate Cox regression analyses of disease-free survival of 307 patients with primary thymoma
From: Long-term outcomes of 307 patients after complete thymoma resection
Variable | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age (years) | ||||||
≤60 | ||||||
>60 | 0.733 | 0.345–1.558 | 0.420 | |||
Sex | ||||||
Female | ||||||
Male | 1.175 | 0.680–2.028 | 0.563 | |||
Tumor size (cm) | 1.017 | 0.913–1.132 | 0.762 | |||
Myasthenia gravis | ||||||
Yes | ||||||
No | 1.254 | 0.610–2.580 | 0.538 | |||
WHO histological classification | ||||||
A + AB | ||||||
B1 | 2.513 | 0.844–7.481 | 0.098 | 1.530 | 0.492–4.759 | 0.463 |
B2 | 6.831 | 2.810–16.604 | <0.001 | 2.855 | 1.070–7.621 | 0.036 |
B3 | 7.999 | 3.032–21.108 | <0.001 | 2.404 | 0.809–7.141 | 0.114 |
Masaoka stage | ||||||
I | ||||||
II | 2.284 | 0.669–7.801 | 0.188 | 1.211 | 0.326–4.501 | 0.775 |
III | 12.624 | 3.800–41.943 | <0.001 | 4.935 | 1.289–18.894 | 0.020 |
IVa | 26.872 | 7.102–101.680 | <0.001 | 13.809 | 3.230–59.043 | <0.001 |
Surgical approach | ||||||
Transthoracic | ||||||
Transsternal | 0.803 | 0.421–1.532 | 0.506 | |||
VATS | 1.304 | 0.635–2.676 | 0.470 | |||
Postoperative radiotherapy | ||||||
Yes | ||||||
No | 2.212 | 1.214–4.032 | 0.010 | 1.887 | 0.932–3.823 | 0.078 |