Fig. 3
From: Id4 promotes cell proliferation in hepatocellular carcinoma
Id4 promoted proliferation and colony formation of HCC cells in vitro. The Cell Counting Kit-8 (CCK-8) assay was performed to examine cell proliferation. a, b Up-regulation of Id4 significantly promotes proliferation of SMMC-7721 and MHCC-97L cells. c, d Id4 knockdown significantly suppresses cell proliferation in Huh7 and PLC/PRF/5. e The number of colonies increased significantly in SMMC-7721-Id4 and MHCC-97L-Id4 groups. f The numbers of colonies decreased remarkably after Id4 silence in Huh7 and PLC/PRF/5groups. *P < 0.05, **P < 0.01, ***P < 0.001