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Table 1 Demographic and clinical characteristics of 460 patients with hepatocellular carcinoma (HCC)

From: Microwave ablation is as effective as radiofrequency ablation for very-early-stage hepatocellular carcinoma

Parameter

RFA group (n = 159)

MWA group (n = 301)

P value

Sex

  

0.209

 Men

132 (83.0)

235 (78.1)

 

 Women

27 (17.0)

66 (21.9)

 

Age (years)a

54.0 ± 11.0

54.2 ± 11.0

0.889

 ≤65

138 (86.8)

255 (84.7)

0.549

 >65

21 (13.2)

46 (15.3)

 

Heredity

  

0.461

 Yes

6 (3.8)

16 (5.3)

 

 No

153 (96.2)

285 (94.7)

 

Etiology

  

0.799

 Cryptogenic

21 (13.2)

38 (12.6)

 

 HBV infection

128 (80.5)

250 (83.0)

 

 HCV infection

8 (5.0)

11 (3.7)

 

 Schistosomiasis

2 (1.3)

2 (0.7)

 

Tumor size (cm)a

1.7 ± 0.3

1.7 ± 0.3

0.335

Tumor location

  

0.150

 Favorable

121 (76.1)

210 (69.8)

 

 Unfavorable

38 (23.9)

91 (30.2)

 

Child–Pugh class

  

0.127

 Class A

140 (88.1)

278 (92.4)

 

 Class B

19 (11.9)

23 (7.6)

 

HBV-DNAb

  

0.076

 Positive

70 (44.0)

107 (35.5)

 

 Negative

58 (36.5)

143 (47.5)

 

 Absent

31 (19.5)

51 (16.9)

 

ALT (U/L)a

38.28 ± 23.22

38.37 ± 26.80

0.960

 <40

113 (71.1)

237 (78.7)

0.059

 40–80

36 (22.6)

57 (18.9)

 

 >80

10 (6.3)

7 (2.4)

 

TBIL (μmol/L)a

17.53 ± 8.33

17.51 ± 8.53

0.979

 ≤20

108 (67.9)

217 (72.1)

0.350

 >20

51 (32.1)

84 (27.9)

 

DBIL (μmol/L)a

6.80 ± 3.91

7.33 ± 4.83

0.236

 ≤7

104 (65.4)

177 (58.8)

0.167

 >7

55 (34.6)

124 (41.2)

 

ALB (g/L)a

40.60 ± 5.49

41.21 ± 5.31

0.243

 <35

25 (15.7)

38 (12.6)

0.358

 ≥35

134 (84.3)

263 (87.4)

 

GGT (U/L)a

85.79 ± 83.51

77.98 ± 113.45

0.445

 <50

89 (56.0)

187 (62.1)

0.125

 50–100

38 (23.9)

75 (24.9)

 

 >100

32 (20.1)

39 (13.0)

 

PLT (×109/L)a

120.37 ± 55.13

122.60 ± 60.00

0.696

 <100

67 (42.1)

122 (40.5)

0.739

 ≥100

92 (57.9)

179 (59.5)

 

PT (s)a

12.9 ± 1.3

12.9 ± 1.3

0.699

 ≤13

101 (63.5)

185 (61.5)

0.665

 >13

58 (36.5)

116 (38.5)

 

AFP level (μg/L)

  

0.144

 <20

69 (43.4)

156 (51.8)

 

 20–200

44 (27.7)

80 (26.6)

 

 >200

46 (28.9)

65 (21.6)

 

CA19-9 (kU/L)

  

0.053

 ≤39

107 (67.3)

228 (75.7)

 

 >39

52 (32.7)

73 (24.3)

 

Hospital stay (days)a

3.4 ± 1.7

3.4 ± 2.3

0.975

  1. RFA radiofrequency ablation, MWA microwave ablation, HBV hepatitis B virus, HCV hepatitis C virus, ALT alanine aminotransferase, TBIL total bilirubin, DBIL direct bilirubin, ALB albumin, GGT gamma-glutamyl transpeptidase, PLT platelet, PT prothrombin time, AFP alpha fetoprotein, CA19-9 carbohydrate antigen 19-9
  2. aThese data are presented as mean ± standard deviation; other values are presented as number of patients followed by percentage in parentheses
  3. bHBV-DNA level of more than 50 copies/mL is considered HBV-DNA positive