Table 3 ASB3 gene mutations in colorectal cancer tissues and cell lines

Colorectal cancer tissues

 CDS 21C→G^a

Nonsense

Exon 2

TAC→TAG ^b

Y7stop

C56

 chr2:53810098 G→C

Splice-site

Exon 3/Intron

–

–

C53

 CDS 404G→R

Missense

Exon 4

GGA→GAA

G135E

S78, S64

 CDS 1084C→Y

Missense

Exon 8

CGC→TGC

R362C

S35

 CDS 1016A→W

Missense

Exon 8

AAA→ATA

K339I

S12, S61, S64

Colorectal cancer cell lines

 CDS 471A→T

Missense

Exon 5

GAA→GAT

E157D

HCT116

 CDS 471A→W

Missense

Exon 5

GAA→GAT

E157D

HT-29

 CDS 24G→R

Synonymous

Exon 2

GCG→GCA

Non

DLD-1

 CDS 25G→K

Missense

Exon 2

GAC→TAC

D9Y

DLD-1

 CDS 154T→Y

Missense

Exon 2

TAT→CAT

Y52H

DLD-1

 CDS 922G→R

Missensee

Exon 7

GCC→ACC

A308T

DLD-1