Variable
|
OS
|
DFS
|
---|
HR
|
95% CI
|
P value
|
HR
|
95% CI
|
P value
|
---|
Invasive depth (T4 vs. T3 vs. T1–2)
|
1.646
|
1.083–2.501
|
0.020
|
1.532
|
1.028–2.283
|
0.036
|
N status (N1–3 vs. N0)
|
2.248
|
1.474–3.426
|
<0.001
|
2.139
|
1.405–3.256
|
<0.001
|
ASPP2 expression (high vs. low)
|
0.541
|
0.363–0.804
|
0.002
|
0.599
|
0.404–0.888
|
0.011
|
P53 expression (high vs. low)
|
–
|
–
|
–
|
2.161
|
1.100–4.245
|
0.025
|
Radiotherapy (yes vs. no)
|
–
|
–
|
–
|
0.575
|
0.374–0.990
|
0.046
|
- – The variables with a P value > 0.05 were not included in the multivariate analysis. Abbreviations as in Table 2