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Table 3 Multivariate Cox regression analysis of predictors for OS and DFS of ESCC patients

From: Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study

Variable

OS

DFS

HR

95% CI

P value

HR

95% CI

P value

Invasive depth (T4 vs. T3 vs. T1–2)

1.646

1.083–2.501

0.020

1.532

1.028–2.283

0.036

N status (N1–3 vs. N0)

2.248

1.474–3.426

<0.001

2.139

1.405–3.256

<0.001

ASPP2 expression (high vs. low)

0.541

0.363–0.804

0.002

0.599

0.404–0.888

0.011

P53 expression (high vs. low)

–

–

–

2.161

1.100–4.245

0.025

Radiotherapy (yes vs. no)

–

–

–

0.575

0.374–0.990

0.046

  1. – The variables with a P value > 0.05 were not included in the multivariate analysis. Abbreviations as in Table 2