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Fig. 1 | Chinese Journal of Cancer

Fig. 1

From: Study protocol of the Asian XELIRI ProjecT (AXEPT): a multinational, randomized, non-inferiority, phase III trial of second-line chemotherapy for metastatic colorectal cancer, comparing the efficacy and safety of XELIRI with or without bevacizumab versus FOLFIRI with or without bevacizumab

Fig. 1

Study design of the Asian XELIRI ProjecT (AXEPT). *All patients from South Korea and Japan will receive concomitant bevacizumab treatment; whereas those from China will be treated either with or without concomitant bevacizumab treatment. ECOG PS Eastern Cooperative Oncology Group performance status. The FOLFIRI arm: intravenous infusion of irinotecan 180 mg/m2, leucovorin 400 mg/m2, and 5-fluorouracil 400 mg/m2 on day 1 followed by a 46-h infusion of 5-fluorouracil 2400 mg/m2, repeated every 2 weeks. The XELIRI arm: intravenous infusion of irinotecan 200 mg/m2 on day 1 and oral administration of capecitabine 1600 mg/m2 per day on days 1–14, repeated every 3 weeks

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Cancer Communications

ISSN: 2523-3548

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