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Table 4 LOH profiles in 10 patients with SHC in the same liver

From: Combined hepatocellular and cholangiocarcinoma originating from the same clone: a pathomolecular evidence-based study

Case
no.
Tumor nodule LOH locus Different LOH Informative loci Different LOH/informative
loci (%)
Clonality
diagnosis
D4S402 D4S406 D17S831 D16S505 D17S938 D8S277 D16S514 D8S520 D8S258 D8S264
1 T1 NI 3 8 37.5 MO
  T2 F     
2 T1 NI NI 3 8 37.5 MO
  T2 NI F     
3 T1 F 3 9 33.3 MO
  T2 F     
4 T1 F 3 8 37.5 MO
  T2 F     
5 T1 F 3 9 33.3 MO
  T2 F     
6 T1 F F 3 8 37.5 MO
  T2 F NI     
7 T1 F F 3 8 37.5 MO
  T2 F F     
8 T1 NI NI F 3 7 42.8 MO
  T2 NI NI NI     
9 T1 F 3 9 33.3 MO
  T2 F     
10 T1 F 3 8 37.5 MO
  T2 F     
  1. SHC separated hepatocellular carcinoma and intrahepatic cholangiocarcinoma, T1 HCC nodule of SHC, T2 ICC nodule of SHC, LOH, ▲ missing but not in the same band, retain, NI non-informative, F not done, SO single clonal origin, MO multiple clonal origins