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Table 3 LOH profiles in 16 patients with CHC

From: Combined hepatocellular and cholangiocarcinoma originating from the same clone: a pathomolecular evidence-based study

Case no. Tumor component LOH locus Different LOH Informative loci Different LOH/informative loci (%) Clonality diagnosis
D4S402 D4S406 D17S831 D16S505 D17S938 D8S277 D16S514 D8S520 D8S258 D8S264
1 T1 NI F 2 8 25.0 SO
  T2 F     
2 T1 NI F 2 7 28.5 SO
  T2 NI F     
3 T1 2 8 25.0 SO
  T2 F F     
4 T1 F 2 7 28.5 SO
  T2 NI F NI     
5 T1 2 9 22.2 SO
  T2 F     
6 T1 NI F 2 8 25.0 SO
  T2     
7 T1 F NI 2 7 28.5 SO
  T2 F     
8 T1 F 2 8 25.0 SO
  T2 NI     
9 T1 NI 2 9 22.2 SO
  T2     
10 T1 F 2 8 25.0 SO
  T2 NI     
11 T1 NI F 2 8 25.0 SO
  T2 F     
12 T1 F 2 9 22.2 SO
  T2 F     
13 T1 F 2 9 22.2 SO
  T2     
14 T1 2 8 25.0 SO
  T2 F NI     
15 T1 NI 2 8 25.0 SO
  T2 F     
16 T1 F 2 8 25.0 SO
  T2 NI     
  1. LOH loss of heterozygosity, CHC combined hepatocellular and cholangiocarcinoma, T1 HCC component of CHC, T2 ICC component of CHC, LOH, ▲ missing but not in the same band, retain, NI non-informative, F not done, SO single clonal origin, MO multiple clonal origins