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Table 1 The characteristics of all single-nucleotide polymorphisms (SNPs) involved in the study

From: Associations of genetic polymorphisms of the transporters organic cation transporter 2 (OCT2), multidrug and toxin extrusion 1 (MATE1), and ATP-binding cassette subfamily C member 2 (ABCC2) with platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients

Gene Location SNP Alleles MAF Call rate (%) HWE P value
OCT2 6q25.3 rs316003 C/T 0.78 (T) 96.28 0.903
rs316019 G/T 0.85 (G) 96.28 0.949
ABCB1 7q21.12 rs1045642 C/T 0.38 (T) 98.26 0.969
ABCC2 10q24 rs717620 G/A 0.19 (A) 95.53 0.766
rs2273697 G/A 0.10 (A) 99.75 0.357
rs3740066 G/A 0.20 (A) 96.77 0.873
MATE1 17p11.2 rs2289669 G/A 0.50 (A) 96.03 0.128
  1. MAF minor allele frequency, HWE Hardy–Weinberg equilibrium, OCT2 organic cation transporter 2, ABCB1 ATP-binding cassette subfamily B member 1, ABCC2 ATP-binding cassette subfamily C member 2, MATE1 multidrug and toxin extrusion 1
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Cancer Communications

ISSN: 2523-3548

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