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Fig. 3 | Chinese Journal of Cancer

Fig. 3

From: EYA4 gene functions as a prognostic marker and inhibits the growth of intrahepatic cholangiocarcinoma

Fig. 3

Tumor-suppressive effects of EYA4 gene expression in vitro. a EYA4-overexpressing transfectants RBE-EYA4 and SSP-EYA4 show significantly elevated expression levels of EYA4 mRNA (*P = 0.001 and *P < 0.001, respectively) as well as protein levels. b Overexpression of the EYA4 gene significantly suppressed the growth rate of RBE-EYA4 and SSP-EYA4 compared with RBE-vector and SSP-vector, respectively (both *P = 0.001). c EYA4-overexpressing transfectants show weaker capacity in foci formation than their vector control transfectants (both *P < 0.001). d EYA4 overexpression resulted in weakened invasiveness of transfectants (both *P < 0.001)

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Cancer Communications

ISSN: 2523-3548

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